Best CBD Products for Stress & Mood

View the top CBD oils for stress and mood support. We review what makes a CBD product useful for various forms of stress and mood problems — and which ones to avoid.

Article By
Justin Cooke , posted 2 months ago

Everyone experiences stress and mood swings from time to time — but there’s a clear distinction between “healthy” stress and “unhealthy stress”.

Too many people in today’s world experience a rollercoaster of emotions, and crippling stress on a daily basis.

Pharmaceutical antidepressants and anti-anxiety medications are among the most widely-prescribed medications on earth. It’s clear a large number of people alive today experience challenges with stress levels and fluctuations in mood.

CBD is now a popular alternative to prescription medications for its ability to provide relief for a wide range of symptoms, without having nearly the same severity of side-effects.

In this article, we’ll review the best CBD oils and other products to use for stress and anxiety, and some insight into how people are using these products today.

  • Table of Contents

CBD For Stress & Mood in A Nutshell

CBD is a great supplement to take alongside stress or various mood disorders.

This unique compound interacts with a system in the body known as the endocannabinoid system — which plays a key role in the stress response and regulation of our mood.

Here’s how CBD can be used for stress and mood support:

  1. CBD alleviates many of the side-effects of stress — including insomnia, digestive issues, poor immune function, loss of appetite or excessive appetite.
  2. CBD Supports Homeostasis throughout the body — improving our overall ability to manage and recover from stressors in the environment.
  3. CBD Promotes GABA activity — GABA helps to slow down hyperactive thoughts and emotions
  4. CBD Supports sleep — which plays a major role in our mood and ability to handle stress
  5. CBD relaxes muscle tension — which is one of the primary physical manifestations of stress on the body
  6. CBD regulates the serotonin receptors — which are a key player in the regulation of mood
  7. CBD buffers our stress response system in the brain — it acts directly on the hypothalamus, improving the response time and accuracy of hypothalamus, pituitary, adrenal axis.

What to Look For When Buying CBD Oils for Stress & Mood

There are a lot of CBD products on the market — making it difficult to know if you’re making the right decision with the product you buy.

Making matters worse is the fact that a large number of the CBD oils being offered are lacking in one area or another.

Some Areas Where a CBD Oil May Fall Short:

  • The potency of CBD is too low — we recommend opting for the higher potency options because it’s easier to dilute a high-potency oil than it is to take large doses of a low-potency oil.
  • Contaminated with heavy metals or pesticides — this is common, and can actually cause chemical stress to the body rather than alleviate it.
  • Oils made with CBD isolates lack the benefits of the entourage effectthe compounds in hemp work together to produce stronger effects. CBD isolates tend to be less effective than full-spectrum extracts.
  • The product lacks other beneficial ingredients — CBD works best with other beneficial extracts. Things like melatonin, L-theanine, or other herbal extracts go a long way in making the oil more effective for stress and mood support.

Best CBD Product for Stress & Mood

NumberProductTotal CBDPotencyCost per mg CBDLink

1

Royal CBD Oil

250 – 1000 mg

8.3 – 33.3 mg/mL

$0.15 – $0.26

2

Nature’s Script High Potency Gummies

75 – 1500 mg

15 – 25 mg/capsule

$0.09 – $0.20

3

Kat’s Naturals Relax THC-Free Sublingual CBD Oil

50 mg – 300 mg

10 mg/mL

$0.20 – $0.36

4

NuLeaf Naturals CBD Oil

240 – 4850 mg

48.5 mg/mL

$0.09 – $0.16

5

Bluebird Botanicals CBD Vape Oil

333 – 1000 mg

33.3 mg/mL

$0.07 – $0.09

6

Medterra Good Morning Capsules

1500 mg

25 mg per Capsule

$0.04

1. Best Overall CBD Oil for Stress & Mood Support

$64.99 – $149.99
Royal CBD

Royal CBD Oil 30 mL

4.5 / 5

  • Total CBD:

    250 – 1000 mg

  • Potency:

    8.3 – 33.3 mg/mL

  • Cost per mg CBD:

    $0.15 – $0.26

  • Extract Type:

    Full-spectrum

  • THC Content:

    <0.3%

The 500 mg oil made by Royal CBD made the top of our list for three main reasons:

  1. It’s a simple formula without any additional ingredients, just high-CBD hemp extract and MCT oil — this is great for use with mood and stress support because it lowers the chances of a compound in the oil negatively interacting with other medications you might be taking.
  2. This oil is made with premium-quality hemp — all Royal CBD hemp is tested in a third-party lab for quality and purity, and again once the final product is complete.
  3. Royal CBD Oils are made with a full-spectrum extract — which has been shown numerous times to be the best option for mood and stress support compared to CBD oils made from an isolate.

2. Best CBD Capsules for Stress & Mood Support

$14.99 – $139.99
Nature’s Script

Nature’s Script High-Potency CBD Capsules – Deleted 60 Count

3.6 / 5

  • Total CBD:

    75 – 1500 mg

  • Potency:

    15 – 25 mg/capsule

  • Cost per mg CBD:

    $0.09 – $0.20

  • Extract Type:

    Isolate

A lot of people supplementing CBD to help them stabilize their mood find that capsules are the most convenient option. They’re easy to use, provide exactly the same doses each time, and can even fit in standard pill containers.

Nature’s Script High-Potency CBD Capsules takes the win in this category because of the high-quality hemp the company is known for. All of these capsules are made from certified organic hemp, and independently lab tested to assess the purity and potency of the capsules.

Each capsule comes with 25 mg of CBD.


3. Best CBD Oil for Anxiety

$19.99 – $59.99
Kat’s Naturals

Kat’s Naturals Relax THC-Free Sublingual CBD Oil 5 mL – 30 mL

3.83 / 5

  • Total CBD:

    50 mg – 300 mg

  • Potency :

    10 mg/mL

  • Cost per mg CBD:

    $0.20 – $0.40

  • Extract Type:

    Isolate

  • THC Content:

    0.0%

Kat’s Natural’s combined other medicinal herb species in with their oils for added potency. Their Relax oil contains hops (Humulus lupulus) — which is a potent relaxant with similar, and complementary effects to CBD (it works primarily through GABA).

In fact, hops is one of the only other members of the cannabis family (Cannabaceae).


4. Best CBD Oil for Low Mood

When it comes to using CBD for low mood, it’s critical that you’re careful about mixing CBD with antidepressant medications — such as SSRIs, tricyclic antidepressants, or monoamine oxidase inhibitors (MAOIs).

In order to minimize the chances of negative interactions, most people use a “pure” CBD oil instead of something formulated with other herbs and supplements.

It’s also important that the dose is always consistent, and that the oil you’re using is completely free from contaminants like heavy metals — which can lead to even worse depression.

This is why we chose Nuleaf Naturals as our favorite CBD oil for depression. They offer some of the highest quality hemp oils on the market, provide only one potency option, and contains no added ingredients aside from the CBD extract and hemp seed oil.


5. Best Vape Oil for Stress & Mood Support

Vaping is a great way to use CBD for supporting stress and mood simply because of its ease of use and fast onset of effects.

At the very first signs of anxiety attacks, or stress, CBD can be vaped to alleviate symptoms within minutes.

We like the vape oils by Bluebird Botanicals for this because of the high-quality hemp source used to make the oil, and the great value. These oils are relatively cheap especially for the level of care and attention that goes into making them.


6. Best CBD Capsule Formula For Mood Support

$55.99
Medterra

Medterra Good Morning Capsules 60 Capsules

4.5 / 5

  • Total CBD:

    1500 mg

  • Potency:

    25 mg per Capsule

  • Cost per mg CBD:

    $0.04

  • Extract Type:

    Broad-Spectrum

  • THC Content :

    0.0%

Medterra makes a lot of great CBD products. One of the best formulas is their Everyday capsules – formulated with 25 mg of CBD per capsule, along with other ingredients like caffeine, L-theanine, B6, B12, and L-Tyrosine.

Each of these ingredients are popular additions to nutritional supplements directed at supporting optimal mood.

Ingredients like caffeine boost energy levels, while CBD, L-theanine, vitamin B, and L-tyrosine optimal support neurotransmitter balance within the brain.

This is an excellent formula from Medterra, perfectly formulated for daily CBD supplementation with the goal of supporting shifts in mood.


What Causes Stress?

“Stress” is the body’s response to a force on the body that requires an adjustment.

Let’s break it down more closely.

Everything in the body is kept within a specific balance.

Temperature, blood pH, hormones, and blood sugar levels are all carefully maintained by the body.

Whenever we face changes in the environment (a stressor) the body needs to make adjustments to keep us in balance. Let’s take the temperature for example — when we step into a hot sauna, the environment starts to heat the body up beyond its ideal range.

Stress is the response from the body to this rise in temperature as it tries to counteract the effects.

We begin to sweat and blood flows to the exterior of the skin to help vent the heat faster, and our metabolism slows down to reduce the amount of heat generated by the body.

Every time the body experiences a stressor, it needs to quickly adapt and respond to the stress. This response is primarily controlled by our limbic system — a region located deep within the brain. The limbic system is responsible for regulating our emotions, instincts, and — of course — our response to stressors in the environment.

However, stress is caused by more than just our environment — even our own thoughts and emotions can lead to stress. This form of stress can be very bad for our health if allowed to persist for long periods of time — leading to the development of mood disorders like anxiety, depression, or bipolar disorder.

There Are Two Main Types of Stress:

  1. Acute Stress — short term stress. This form of stress happens quickly to help us manage dangerous situations (such as coming face to face with a hungry tiger).
  2. Chronic stress — long term stress. This is the more common form of stress we see in today’s society. It’s usually caused by ill health, or more abstract causes of stress like financial debts, the pressure to perform at work or school, and relationship troubles.

What Makes Stress Bad For Our Health?

Normally, our body’s are well adapted to manage stress — it’s even considered a key element of good health. If we’re exposed to too much stress for the body to adapt, we can become very sick — this is essentially what going into shock involves.

On the other side of this, if we’re exposed to stress for long periods of time, we begin to lose our ability to cope — leading to negative effects on our physical and mental health.

Think of stress resistance like a bank account:

Every day you get a deposit into your account for $100 — this is the ability for our limbic system to handle the stresses we’re exposed to.

Now every time we experience a stressor, we have to spend some money from our bank account. Ideally, we’ll finish the day with some of this cash leftover in our bank account.

When we’re under near-constant stress — like most people alive today — we end up with a negative balance at the end of the day. Like any good bank, there’s an interest fee when we’re in the negative range.

This means that the next day we need to work extra hard to conserve our exposure to stressors otherwise we’ll end up even further in “stress debt”.

Eventually, we reach a point where we no longer have the capacity to handle even small stresses — causing us to experience side-effects like depression, anxiety, adrenal fatigue, immune dysfunctions, and more.

Although there are a lot of different hormones involved with the stress response, the most relevant in terms of mood is cortisol — the chief “stress hormone” in the body.

Cortisol is what causes many of the changes we experience when we’re stressed. It’s designed to help us make the changes we need to handle stress. However, there are some tradeoffs — one of them being that it can force the balance of mood-regulating neurotransmitters in the brain out of balance.

High cortisol levels for long periods of time lead to elevations in neurotransmitters like norepinephrine and glutamate, and a gradual loss of serotonin and dopamine.

Both serotonin and dopamine play a critical role in regulating our mood. These are the key focus of pharmaceutical antidepressant drugs in the treatment of mood disorders.

When cortisol levels force the neurochemistry of the brain to change too often (long term stress), or with too much force (traumatic event) — it can lead to sustained losses of serotonin or dopamine — leading to chronic depression or bipolar disorder.

Anxiety is also a common result of chronic stress. Cortisol stimulates the activity of neurotransmitters like glutamate that have a stimulating effect on the brain. If this excitation is too strong, we experience anxiety. This is why anxious people are more easily triggered by small stresses than healthy individuals.

As we fall further into “stress debt”, the problem compounds on itself — leading to hyperactivation of the stress response, higher cortisol levels, and further changes to the normal neurochemistry of the brain.

Mood Disorders Associated With Long-Term or Excessive Stress

  • Generalized anxiety disorder
  • Social anxiety disorder
  • Bipolar disorder
  • Depression
  • Post Traumatic Stress Disorder (PTSD)

How to Use CBD for Mood & Stress Support

Using CBD for supporting our mood and stress levels is fairly straightforward. As long as we’re getting the right dose (more on how to do this later), and stay away from low-quality or contaminated CBD products — were likely going to experience at least some improvement on our stress levels and mood.

However, if you follow this simple 4 step process, you can truly dial in your CBD supplementation to get as much benefit as possible out of your CBD.

Step 1: Read Reviews on the Products You Want Before You Buy Them

The CBD market is brand new and still lacks a lot of the regulation needed to keep bad products out of the marketplace. This makes it easy for companies to sell really poor-quality CBD oils at a high markup — making a quick buck in the meantime. By the time regulation works its way in, these companies will simply step out of the market and count their cash.

Reading reviews on your products is a good way to get unbiased information and opinions on the products by people who know exactly what to look for and how to assess it.

Factors to Consider When Buying CBD:

  • Third-party test results
  • Product potencies
  • Additional information about the company
  • Quality of the hemp being used
  • Customer service responsiveness and knowledge
  • Additional ingredients list

Step 2: Dial-In the Dosage

If you’ve never used CBD before, you’re going to need to read this step extra carefully.

The correct dose of CBD to use will vary a lot from person to person.

Size, weight, genetics, experience using CBD, liver metabolism, and age can all affect the dosage of CBD. Therefore, we can only really provide basic ranges in the dosage — everybody needs to spend some time calling their dose in when they start using CBD for the first time.

This is done by starting at the low range of their general dosage range and monitoring the effects. From here, you can increase the dose slightly each time until you reach your desired effects.

If you experience side-effects, simply dial the dose back to the last time you didn’t.

Over time the dose can change, but once you get a feel for how your body responds to the CBD, you’ll be able to make adjustments on the fly.

Here are some very general dosage ranges separated by weight, and strength level:

Weight (lbs)Low StrengthMedium StrengthHigh Strength

100 lbs

10 mg

30 mg

60 mg

125 lbs

13 mg

38 mg

60 mg

150 lbs

15 mg

45 mg

90 mg

175 lbs

17 mg

52 mg

105 mg

200 lbs

20 mg

60 mg

120 mg

225 lbs

22 mg

67 mg

135 mg

250 lbs

25 mg

75 mg

150 mg

These doses are in mg of CBD. You may take anywhere from 1 dose of CBD, to 3 doses in a day depending on your symptoms and how long the effects of the CBD last for you. Most people report about 8 hours of effects.

Learn more about dosing CBD.

Step 3: Monitor Any Changes

It’s a good idea whenever taking any medication or supplement for stress and mood levels. Keeping track of your dosing, and any changes— both good and bad — are extremely helpful for dialing you’re supplementing in, and tracking the effectiveness (or lack thereof).

Mood and stress are very broad — it can be hard to tell if there’s any improvement or not on a day to day basis. For this reason, we recommend you quantify your feelings on a regular basis so that you or your doctor can look back on your progress after a few weeks, and months.

To do this, simply keep some notes in a journal, or on your computer. Set a timer on your phone to go off at a specific time once per week to remind you to fill out these notes.

You can write down some simple questions of your own to answer, use our sample at the bottom of the section, or find an official version to use online.

These questions should only take 1–5 minutes to complete depending on which one you use.

Some Sample Questions to Ask to Monitor Your Progress with CBD

  1. Rate your stress on a scale of 1 to 10
  2. Rate your mood on a scale of 1 to 10
  3. Rate the average quality of your sleep on a scale of 1 to 10
  4. Describe your mood today in a sentence
  5. How many times have you exercised this week?
  6. What was your daily dose of CBD?
  7. What other supplements did you take this week?

Note: 1 is the lowest on this rating, and 10 is the highest. A 1 stress rating would be you at your most relaxed and calm, while a 10 would mean you feel like you’re running away from a lion.

You can use modifications of this list as daily, weekly, or monthly questions.

CBD can take a few weeks for some people to begin experiencing its benefits, so remember to be patient, and keep monitoring how you feel.

Wait until you’ve been using the CBD oil on a daily basis for a few weeks to really know how it works for you (or not).

Other Supplements to Mix CBD With For Optimal Benefits

All herbal medicine is better when used in combination with other herbs — especially if the herbs used are synergistic with each other. This means that the effects of the herbs compound off each other to produce stronger results in combination than either of them on their own.

When it comes to combining CBD oils or other products with synergistic herbs and supplements, there are a few that you should at least be aware of:

1. Rhodiola

Rhodiola (Rhodiola rosea) is a small succulent found growing at high altitudes around the world. These plants live in some of the most remote corners of the world, thriving in environments where most other organisms would quickly perish.

This herb was made famous for its use in secret Soviet research programs in the 1950s and 60s. Soldiers were given rhodiola to enhance their ability to adapt and survive in harsh environments. Sometime in the mid-60s one of the lead researchers escaped Russia to the United States where he shared a lot of the findings.

Since this time rhodiola has become one of the most important adaptogenic supplements on earth — buffering the brain’s receptiveness to cortisol to give us a better ability to resist and manage stressors in our environment.

Rhodiola is mildly stimulating and is best for people experiencing stress from athletic exertion, long workdays, or depression involving fatigue.

(Rhodiola rosea)

2. Ashwagandha

Ashwagandha (Withania somnifera) is another adaptogenic herb with a long history of medical use. This particular herb works more specifically on the adrenal glands where cortisol is produced. It supports the adrenal function — helping prevent burnout from excessive cortisol and catecholamine production and lowering our perceived stress level.

Ashwagandha is considered more relaxing and is better for people experiencing stress along with anxiety or insomnia.

3. L-Theanine

L-theanine is an extract from the tea plant (Camellia sinensis). It’s structurally similar to glutamate — the primary stimulatory neurotransmitter in the brain.

By mimicking glutamate, L-theanine is able to bind to the glutamate receptors and block real glutamate from attaching itself and activating the neuron. The end result is a potent relaxing effect on the mind, without making us feel sluggish, or tired.

L-theanine is popular for alleviating the stress associated with long work or school sessions and can even be used to support memory and concentration. It’s also one of the best supplements to take alongside CBD oil for anxiety-related conditions.

(High-Grade Green Tea — the Source of L-Theanine)

4. St. John’s Wort

St. John’s Wort (Hypericum perforatum) is arguably the best antidepressant herbal medicine on earth. It works through the same mechanism as conventional pharmaceutical antidepressants like SSRIs, only without producing the same level of side-effects.

This herb should be used cautiously and never combined with pharmaceutical antidepressants. The effects are so similar it can cause too strong of an effect — which can be dangerous.

Only use St. John’s wort with mild depressive symptoms, or under the supervision of a trained medical professional.

(St. John’s Wort — Hypericum perforatum)

Key Takeaways: Best CBD Oils for Stress & Mood Support

CBD is an excellent health supplement to take for stress and mood support.

The compound works through a series of related, and unrelated receptors and cell-signaling mechanisms to enhance our ability to resist, and respond to the stresses exerted on us in our environment and from our own thoughts and emotions.

By buffering our ability to resists stress we can also impact our mood. Additionally, CBD offers effects on mood through its ability to modulate serotonin, dopamine, norepinephrine, GABA, and glutamate — both directly and indirectly.

The best CBD oils for stress and mood support are rigorously tested to prove the absence of contaminants that can worsen the condition, and use a premium full-spectrum hemp extract instead of CBD isolates.

Depending on the specific condition or symptoms, it’s usually better to choose a high-potency option, and something with additional ingredients designed to make the overall formula even stronger.

As always, be sure to start CBD oil or other forms of CBD at a small dose if trying it for the first time. You can then increase the dose gradually from there once you understand how your body responds.

Top-Rated CBD Mood & Stress Products

NumberProductTotal CBDPotencyCost per mg CBDLink

1

Royal CBD Oil

250 – 1000 mg

8.3 – 33.3 mg/mL

$0.15 – $0.26

2

Nature’s Script High Potency Gummies

75 – 1500 mg

15 – 25 mg/capsule

$0.09 – $0.20

3

Kat’s Naturals Relax THC-Free Sublingual CBD Oil

50 mg – 300 mg

10 mg/mL

$0.20 – $0.36

4

NuLeaf Naturals CBD Oil

240 – 4850 mg

48.5 mg/mL

$0.09 – $0.16

5

Bluebird Botanicals CBD Vape Oil

333 – 1000 mg

33.3 mg/mL

$0.07 – $0.09

6

Medterra Good Morning Capsules

1500 mg

25 mg per Capsule

$0.04

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