Bipolar disorder involves severe fluctuations in mood. CBD provides benefits for a range of mood disorders, including bipolar disorder. Here’s how it works.
Bipolar disorder affects between 0.4% and 1.6% of the world’s population, according to recent reports. This means roughly 70 million people around the planet suffer from bipolar disorder to some degree.
There are treatment options available — however, they often come with a myriad of negative side-effects, and often don’t work at all.
This prompted researchers to explore new treatment options. One of the compounds gaining a lot of attention as a potential new treatment for bipolar disorder is cannabidiol — one of the primary phytochemicals in the cannabis plant.
Cannabidiol, or CBD as it’s commonly known, has been shown to protect the brain from damage and support healthy neurotransmitter function. Through these effects, it’s believed to reduce the severity of the bipolar disorder and help those affected to maintain more stable moods throughout the day.
Here, we’ll explore the role CBD plays in maintaining mood, how to use CBD for bipolar disorder, and when to avoid it.
Let’s get started.
Using CBD for bipolar disorder isn’t a new concept, and there’s currently one phase II clinical trial underway comparing the long-term effects of CBD with the effects of a placebo in patients diagnosed with bipolar disorder.
In order to get to this stage of research, CBD needed to pass similar tests with flying colors. If it failed any of the studies prior to this phase II clinical trial, it wouldn’t have been approved for use in the study.
Previous studies found that CBD offers a clear benefit to mood disorders with little to no side-effects.
Although there are clear benefits to using CBD with bipolar disorder, there are some important cautions to be aware of before deciding if it’s right for you or not.
Some cannabinoids in the cannabis plant, including THC, can actually make bipolar disorder significantly worse. Therefore, it’s critical that the CBD product you purchase contains low levels of THC to avoid this.
For bipolar disorder, it’s recommended that only a high-grade, full-spectrum extract with third-party lab testing to confirm the cannabinoid profiles of the product is used.
The other option is to use a CBD isolate — which contains nothing but active CBD.
Bipolar disorder is usually treated with powerful antipsychotic drugs. These medications alter neurotransmitters in the brain. Users need to be cautious when taking other supplements, including herbs and nutritional supplements such as CBD oil because it can be difficult to predict how they interact with prescription medications.
Always consult your doctor before trying CBD for bipolar symptoms to check for drug-herb interactions.
Bipolar disorder is characterized by dramatic changes in mood, behavior, and energy levels.
The root of the condition is the balance of neurotransmitters in the brain. Neurotransmitters such as serotonin, dopamine, GABA, glutamate, and others all fluctuate and interact throughout the day to regulate our moods.
Everybody’s mood fluctuates to some extent — we have periods of feeling joy and periods of discomfort and irritability. This is normal — however, in bipolar patients, these fluctuations are far more severe, often making it difficult to perform daily activities such as complete work or socially interact.
The specific neurotransmitters responsible for bipolar symptoms can vary, and in many cases, the exact cause is never truly identified.
This makes the condition hard to treat, and much of the treatment in a hospital is done through trial and error — patients try a drug and wait to see if it produces results. If not, they try the next one in line until they find something that relieves their symptoms.
Bipolar disorder causes episodes of extreme emotion that can last anywhere from a few minutes to a few weeks at a time. Episodes can range from mild to extreme.
There are three primary types of episodes experienced by those with bipolar disorder.
The brain is in a state of hyperactivation, which can make people seem intense or overly happy. During manic episodes, those affected tend to have a lot of energy. They can seem highly motivated and euphoric and tend to develop side-effects such as anxiety and insomnia.
Manic episodes can become dangerous as they can make people reckless and may bring negative side-effects such as paranoia, psychosis, or delusions.
A hypomanic episode is similar to a manic episode — but tends to be less extreme. It’s often considered a halfway point between mania and depression.
People experiencing hypomania are often able to continue their normal responsibilities, but find it more challenging to avoid distraction or bursts of anxiety.
Major depressive episodes are the opposite of manic episodes. It causes those affected to have low motivation. They may feel tired and sluggish and can feel severely depressed. They often go through periods of social isolation, and some experience thoughts of suicide or death.
There’s no single cause of bipolar disorder. It’s a combination of many factors ranging from genetic inheritance to environmental and social influences.
Treating bipolar disorder is difficult because the cause is hard to determine.
The best treatment for the condition comes in the form of psychiatric therapy to determine potential triggers and underlying causes such as a history of abuse or mental stresses.
Other causes, such as hormone imbalances, should also be tested for and treated as necessary.
In terms of symptomatic support, there are a few pharmaceutical medications used for treating bipolar disorder.
CBD alleviates many of the common symptoms of bipolar disorder. However, there are also reports of people who had their symptoms magnify due to cannabis use. This is mainly due to the THC content in marijuana, which is neuro-stimulating and can aggravate symptoms.
For this reason, it’s not safe for people with bipolar disorder to consume marijuana that has a high THC content.
It’s also crucial that you speak with your doctor before taking CBD for bipolar disorder to make sure the compound won’t interact negatively with the medications you’re taking.
Once your doctor has approved you to start taking CBD to alleviate symptoms of bipolar disorder, you need to find the right product to use and determine the best dose.
There are many different ways you can take CBD. Here, we’ll discuss the most common options in detail and how they can be used alongside a bipolar diagnosis.
CBD oils and tinctures are the most common forms of CBD supplementation because they simplify dosing.
They’re made by mixing a CBD extract with oil or alcohol. They’re easier to consume because pure CBD or cannabis resin comes as tiny crystals or a sticky, oily, resin — both of which make it difficult to measure the dose accurately.
As an oil, the dose is measured by counting the number of drops using the provided dropper.
CBD oils and tinctures come in a variety of potencies. It’s recommended that you choose a potency that best matches the dose you aim to take. Use our dosage chart in the next section to find your approximate dosage.
CBD capsules provide another popular method of consuming CBD. They take away a lot of the guesswork when it comes to dosing and make it easy to take your CBD on the go.
CBD capsules also come in both low-potency and high-potency options.
Edibles are a great option for people who don’t like the taste of the oils or tinctures and want to avoid swallowing capsules.
The only downside to edibles is that the amount of CBD they contain is often unreliable, making dosing inconsistent.
For a condition such as bipolar disorder, it’s important to be consistent with your CBD use — something that edibles aren’t always able to provide.
Vaping CBD provides the most efficient form of dosing because bioavailability through the lungs is much higher than it is through the digestive tract.
Vaping is a good option for people with bipolar disorder because it offers fast relief from symptoms. It’s also one of the most portable methods of taking CBD.
Deciding on the right dose of CBD can take some trial and error. Everybody responds to this compound differently, so a little bit of self-testing is needed to find the right dose. This is also the case with most of the pharmaceutical bipolar medications used.
It’s best to start with a low dosage and build up gradually over time until you find relief from your symptoms.
In most cases, people with bipolar disorder won’t start to experience benefits until they reach the medium- or high-strength doses. Some people even require doses outside the listed range. The only way to find out your dose is to test it.
|Low-Strength CBD||Medium-Strength CBD||High-Strength CBD|
|• Mild depression or anxiety |
• Periods of higher-than-average stress
• Daily maintenance dose for asymptomatic bipolar disorder
|• Moderate bipolar symptoms |
• High stress
|• Severe bipolar symptoms |
• Severe insomnia
Most bipolar patients take a medium- or high-strength dose of CBD — however, this can vary from one person to the next.
The best way to calculate the dose according to strength is to use the formulas below.
|Unit of Measure||Low Strength||Medium Strength||High Strength|
|Imperial (pounds)||1 mg for every 10 lbs||3 mg for every 10 lbs||6 mg for every 10 lbs|
|Metric (kilograms)||1 mg for every 4.5 kg||3 mg for every 4.5 kg||6 mg for every 4.5 kg|
To make this more simple, we’ve provided a chart using the calculations above.
|Weight (lbs)||Low Strength||Medium Strength||High Strength|
Although CBD is proven to be highly safe in terms of toxicity, it’s important to know about the potential side-effects. Everybody is different, and what works for one person doesn’t always work the same way for another.
Bipolar disorder can severely interrupt normal daily activities and is difficult to treat effectively.
Many people are now turning to CBD as a means of alleviating their symptoms. It works in a few different ways related to hormones, neurotransmitters and central nervous system homeostasis (balance). It also helps to alleviate common side-effects such as muscle tension, insomnia, anxiety, and depression.
The most important thing to remember when taking CBD supplements for bipolar disorder is to first consult with your doctor(s) and avoid any supplement or cannabis containing high amounts of THC. This is very important, as THC can make symptoms of bipolar disorder far worse.
We’ve found that most people find the relief they’re looking for with either a medium- or high-strength CBD supplement.