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The Brothers Apothecary Sleep Aid Capsules

These Sleep Aid Capsules are one of the few products on the market using raw, unadulterated herbs in the formula — there’s no CBD extract in these capsules, just raw hemp, melatonin, and three other herbs. The other ingredients have a strong synergy with hemp, which amplifies the effects to make this a particularly useful sleep supplement — despite the low CBD content. This product is formulated with valerian, chamomile, skullcap, and melatonin — all of which are effective sleep supportive agents in their own right. 

Price/Value 5/5

The average price per mg of full-spectrum CBD on the market is $0.12. The CBD in these capsules is derived from whole hemp flower — not extracts — making it inherently full-spectrum. This reduces its cost without compromising quality at $0.07-0.09 per mg of CBD. The sleep-promoting herbs in these capsules add great value to the purpose of this formula.

CBD Potency 3/5

These are considered low-potency capsules with only 8 mg of CBD per cap. However, these capsules use the whole hemp for the full-spectrum entourage effect in conjunction with sleep-supporting herbs, which all work in synergy to boost its effects to promote sleep. 

Hemp Source 4/5

The Brothers Apothecary exclusively uses Department of Agriculture licensed hemp-derived CBD grown organically in Oregon. We can’t give this source a 5/5 rating yet because it doesn’t have USDA organic certificate — however, Oregon doesn’t offer this certificate to hemp growers. The Brothers Apothecary has a subpage dedicated to its lab testing transparency to prove the hemp used is of high-quality.

Purpose/Uses 5/5

This product has a very specific use and purpose. As the name suggests, these capsules are formulated to support sleep. Its ingredients and CBD content are appropriate for its recommended use.

Product Variations 4/5

These capsules are a niche product. We didn’t expect to see any other variations in terms sizes or flavors, but The Brothers Apothecary does offer these capsules in two bottle sizes — 21-capsules (1-3 week supply) and 84-capsules (4-12 weeks supply). The Sleep Aid Capsules are one of six different capsule formulations in The Brothers Apothecary catalog, each formulated to target a specific health concern.

Formula 5/5

This is one of the best formulas we’ve come across when it comes to CBD sleep supplement. It includes high-grade full-spectrum hemp, several sleep-promoting herbs, and a plant-based lipid to increase the CBD’s bioavailability through ingestion. We have to hand it to The Brothers Apothecary for this well-considered formula.

The Brothers Apothecary CBD Sleep Aid Capsule Review

Article By
Dylan James , last updated on November 16, 2021

Sleep hygiene is an essential component of a healthy lifestyle.

Research shows missing as little as an hour of sleep a night can result in a noticeable difference in mood and cognitive performance.

People who suffer from sleep deprivation often report experiencing high levels of stress.

Stress is a natural response and expresses itself as an increase of the hormone, cortisol, which can make it difficult for the mind to settle down to fall asleep at an appropriate time.

Overview: CBD Sleep Aid Capsules

These CBD Sleep Aid capsules have an excellent formula for promoting a good night’s sleep — we’ve tested it ourselves.

The Brothers Apothecary is a Portland-based company founded by two brothers who have a passion for natural wellness and cannabis. The brand’s expertise in natural wellness shines in the Sleep Aid Capsules.

While CBD is quickly becoming a popular sleep support aid, one of the challenges of shopping for CBD supplements is finding a reliable product in the abundance of poorly formulated product offerings.

The Brothers Apothecary Sleep Aid Capsules contain full-spectrum CBD, valerian root, chamomile, skullcap, and melatonin — all of which are said to work in synergy to help you fall asleep and keep you in a deep sleep throughout the night.

Pros & Cons

Pros Cons
  • Includes a lipid for better CBD absorption
  • Full-spectrum whole hemp flower
  • Contains synergistic ingredients to enhance the effects of CBD for sleep
  • Some may experience a negative reaction to valerian and melatonin
  • Very low CBD potency

Key Features & Benefits

1. CBD May Improve Sleep Quality

The effects of CBD on sleep include:

  • Supports relaxation
  • Relaxes tight muscles
  • Reduces excessive stress reactions
  • Improves hypothalamic function
  • Protects the body from oxidative stress
  • Promotes “rest-and-digest” portion of the nervous system

CBD directly interacts with the body’s endocannabinoid system, which is involved in regulating a variety of physiological and cognitive processes, including the system that deals with our stress response. This will, in turn, greatly improve the quality of your sleep.

2. Formulated With Sleep-Promoting Herbs

The Brothers Apothecary offers a CBD sleep-aid capsule that includes sleep-promoting herbs to “help reduce anxiety, insomnia, tension, and other pains that can keep you up at night.”

These sleep-promoting herbs include melatonin, skullcap, valerian root, and chamomile. CBD has many different health benefits because it interacts with our endocannabinoid system, which helps maintain homeostasis (balance) in many systems in our body.

When CBD is combined with therapeutic herbs, these compounds can work synergistically to produce a more targetted action.

About The Company: The Brothers Apothecary

Two real-life brothers, Shane, and Jesse Richardson, established The Brothers Apothecary in 2015 as Portland’s first CBD tea company.

The brothers share a background in natural wellness and were looking to make wholesome, minimally processed CBD products amongst the high-CBD extract vape pens, gummies, and concentrates.

Instead of using extracts like most CBD brands, The Brothers Apothecary uses whole high CBD hemp flower in most of its products to maintain the plant’s natural cannabinoid and terpene profile for the entourage effect. The brand’s focus is to create products that use hemp the way it has been used for centuries — as a herb.

Today, The Brothers Apothecary has expanded its tea line up and now offers topical CBD formulas, THC-free, and tobacco-free smokable blends, CBD-infused honey, and capsule blends.

The Brothers Apothecary is an all-around great company, and it’s one we recommend for those looking for a more all-natural approach to their CBD supplementation.

The Brothers Apothecary

4.83 / 5

Who Should Consider Using CBD Sleep Aid Capsules?

The Brothers Apothecary Sleep Aid Capsules are formulated for those who experience difficulty sleeping.

Although there is a difference between the type of insomnia that’s characterized by trouble initiating sleep from insomnia involving frequent waking — this formula is strong enough to work on both.

The hemp used contains less than 0.3% THC, so you won’t have to worry about psychoactive effects, and the other herbs included are well tolerated in the formulated amounts.

That being said, there are some people who may react to valerian and melatonin in the opposite way — both of these can make some people feel stimulated — which will interfere with your plans of getting a good night’s sleep. This interaction is very rare, but something to consider nonetheless.

We recommend starting with the lowest possible dose — one capsule – before increasing to anything larger. This is a good practice in general when using a new supplement for the first time.


These Sleep Aid Capsules are available in two sizes — 21-capsules (1-3 week supply) and 84-capsules (4-12 weeks supply).

In order to compare prices across different brands, we divide the cost of the product by the amount of CBD it contains.

Of course, there are many other factors that affect the price including hemp quality, third-party testings, additional ingredients, and associated charities — however, this gives us a baseline for price comparison.

Cost Breakdown of The Brothers Apothecary Sleep Aid Capsules

Product Image Product Name Total Price Total CBD Content Cost per mg CBD Cost per capsule
The Brothers Apothecary CBD Sleep Aid Capsules – 1 oz. bottle (21 capsules) $15.00 168 mg $0.09 $0.70
The Brothers Apothecary CBD Sleep Aid Capsules – 4 oz. bottle (84 capsules) $49.99 672 mg $0.07       $0.60

The average full-spectrum CBD capsule on the market rings in at $0.12 per mg of CBD. The Brothers Apothecary offers excellent value for these Sleep Aid Capsules.

The low cost could be attributed to the minimal processing of The Brothers Apothecary hemp.

This brand isn’t interested in extracts. It believes in wholesome hemp products and in maintaining the cannabinoids and terpenes of the hemp plant. You’ll find most of its products use whole hemp flower for its CBD to maintain the synergistic effects of hemp’s phytonutrients.


Using whole hemp flowers (instead of extracts) makes it difficult to get a precise CBD content, but third-party lab results show there is roughly 8 mg of full-spectrum CBD per capsule, which is considered low for the sleep-enhancing effects of CBD.

However, it seems to be the perfect dose for its context as a gentle sleep formula — most likely due to the interaction, CBD has with other ingredients in the formula.

Most CBD products on the market are formulated with extracts — this involves stripping the organic plant matter from the cannabinoids.

When you have a whole hemp extract like this, you maintain the plant’s natural range of cannabinoids that work synergistically to produce a phenomenon called the entourage effect, increasing the effects of CBD and other phytocannabinoids.

Moreover, the herbs added to these capsules complement CBD’s effects as an anti-anxiety compound.

These capsules contain hemp flower with an estimated amount of 8 mg of CBD per capsule — it’s estimated because it can be difficult to remain consistent from one natural product to another.

We noticed this discrepancy in the product’s packaging as well. It says to have an estimated 8 mg of CBD per capsule, yet the 84-capsule label says there is at least 728 mg of CBD per bottle. This number should say 672 — which is a good indication of how difficult it can be to be precise when dealing with raw herbs instead of concentrated extracts.

Potency Breakdown of The Brothers Apothecary CBD Sleep Aid Capsules

Product Image Product Name Total CBD Content CBD Concentration (mg/capsule) Potency Level
The Brothers Apothecary CBD Sleep Aid Capsules – 1 oz. bottle (21 capsules) 168 mg 8 mg/capsule Low
The Brothers Apothecary CBD Sleep Aid Capsules – 4 oz. bottle (84 capsules) 672 mg 8 mg/capsule Low

Hemp Source

We appreciate The Brothers Apothecary’s transparency when it comes to its hemp. All of The Brothers Apothecary products are made with locally sourced organic hemp crops in Oregon. There’s a whole subpage dedicated to the Apothecary’s testing on its website.

The Brothers Apothecary conducts tests on its products both in-house and with third-party labs.

On its lab testing page, you’ll find resources to help you understand the lab tests and why it’s important to the brand.

While the Certificate of Analysis shows the hemp crops are free from pesticides and heavy metals, verifying its organic claims, it doesn’t have the USDA organic certification.

This isn’t the fault of the company.

Oregon doesn’t provide USDA organic certifications to hemp growers yet, but you can rest assured Brothers Apothecary sources the best crops locally for its products.


As the product name implies, these capsules are designed to help you with sleep issues. This may include:

  • Trouble falling asleep
  • Trouble staying asleep
  • Waking up feeling unrefreshed
  • Jetlag
  • Anxiety before bed

The additional herbs in this formulation are excellent for slowing down an anxious mind, helping you fall asleep and stay asleep, and getting your sleeping pattern back to normal.

Product Options & Flavors

The Sleep Aid Capsules are one out of the six capsule formulations The Brothers Apothecary offers.

Since these Sleep Aid Capsules are a niche product, we didn’t expect to see this product in different flavors or sizes.

The Brothers Apothecary does offer these capsules in different bottle sizes — 21-capsules and 84-capsules — with a slightly discounted price per capsule when you buy the larger supply option.


While CBD is proven effective for supporting a variety of symptoms, it’s more effective when combined with other herbs to target this effect in different ways. The effects of herbs like chamomile also provide sleep-supportive benefits compound with the effects of CBD.

This happens through a concept called synergy.

The basic idea is that the effects of the compounds that are synergistic with other compounds in the formula combine themselves to produce a level of effects greater than the sum of its parts.

What does this mean, you ask?

Well, imagine each ingredient offers +1 to the overall effect of the formula. In the case of these sleep aid capsules, there are 5 main ingredients:

1 + 1 + 1 + 1 + 1 = 5

The sum of these effects should be around 5 in this analogy.

When you get synergy between the ingredients these effects begin to change — the formula would look something more like this:

1 + 1 + 1 + 1 + 1 = 20

The combined effects of all the different ingredients end up being much higher than simply adding them together one by one.

The Brothers Apothecary make great use of this concept in this formula. The CBD interacts very strongly with the other ingredients of the formula — due to similar effects on neurotransmitters like GABA or melatonin, and through competition with metabolic pathways designed to break these ingredients down.

The result is a CBD product that feels much stronger than the amount of CBD content listed. There is only 8 mg of CBD in these capsules, yet this product feels very similar to a large 20 or 30 mg dose of pure CBD — all thanks to the synergy of the cannabinoids and complimentary sleep-aid herbs.

Analyzing the Ingredients of The Brothers Apothecary Sleep Aid Capsules

Ingredient mg per Capsule Effects
High CBD Hemp 8 mg of CBD Manages symptoms associated with disrupted sleep by reducing anxiety
Valerian root 50 mg Also called “nature’s Valium,” valerian root contains compounds that help reduce anxiety through its interaction with GABA receptors
Chamomile 25 mg Often used as a sleep inducer for its sedative effect from the benzodiazepine-like compound found in the flower head
Skullcap 25 mg Used to treat nervous exhaustion, seizures, anxiety, insomnia, nightmares, and cold/flu symptoms.
Melatonin 3 mg Commonly used to treat jet lag, melatonin is a hormone found naturally in the body that lets your body know it’s time to sleep.

The Brothers Apothecary Shipping & Return Policy

The Brothers Apothecary offers international shipping. Most items are shipped via USPS Priority Mail.

If you’re not happy with your product, contact The Brothers Apothecary customer service team at [email protected]. They will provide refunds on unopened products and are happy to do exchanges on a case-by-case basis.

Final Verdict: We Highly Recommend The Brothers Apothecary Sleep Aid Pills

This is perhaps the best sleep-supporting CBD formulation we’ve come across on the market. The brand stays true to its mission to produce high-quality cannabis wellness products with minimal processing.

The Brothers Apothecary clearly understands natural wellness, and it shines in this product.

These capsules contain the right amount of full-spectrum CBD, a blend of sleep-promoting herbs, and a plant-based lipid to make CBD more bioavailable when ingested.

If you’re looking for a more natural way to improve your sleep hygiene, these capsules are worth a try.

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The Brothers Apothecary

4.83 / 5