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Best CBD Company Reviews: Top CBD Oil Brands & Manufacturers [2021]

Palmetto Harmony CBD Suppositories

Suppositories are an excellent way of delivering relatively high doses of CBD directly into the lower digestive tract or vaginal cavity where it can be used to support painful inflammatory conditions. 

CBD suppositories aren’t very common and tend to be very expensive for being such a niche product. Palmetto Harmony’s version is affordable and made from exceptionally high-quality organic hemp extract. This is one of our top-rated CBD suppositories worldwide. 

It’s wise to consult with a health practitioner if you have any reason for using CBD suppositories to rule out any serious underlying health conditions. 

Price/Value 5/5

Palmetto Harmony CBD suppositories are great value for money. They’re made with full-spectrum, third-party-tested CBD and only cost $0.28 per mg. Many other suppositories can cost upward of $0.50 per mg of CBD.

CBD Potency 5/5

Containing 10 mg of CBD per suppository, these are on the lower end of the potency spectrum.

However, rectal tissue is highly effective at absorbing CBD, which makes suppositories a good option for people who are unable to use other CBD products, or those with symptoms specific to the rectal or vaginal cavities. 

Hemp Source 5/5

All of Palmetto Harmony’s CBD products are made with non-GMO, organic, US hemp. The company tests every batch for cannabinoid content, terpenes, heavy metals, pesticides, and more.

In fact, as of May 2019, the Palmetto Harmony became the first CBD company to be awarded the prestigious United States Department of Agriculture (USDA) Certified Organic stamp of approval – an accolade that’s pretty big news within the CBD industry.  

Purpose/Uses 5/5

The shape, and consistency of these suppositories are perfect for insertion into small cavities of the body. As such, this product type is highly specialized for lower digestive tract disorders or inflammation of the vaginal canal. Although the dose of CBD is lower than others in this category, these products are perfect for people sensitive to CBD or other cannabinoids. 

Product Variations 4/5

Although Palmetto Harmony only sells one CBD suppository, there are only a handful of companies that sell them in the first place. However, we would like to see a higher-potency option for those with high daily CBD requirements.

Formulation/Ingredients 4/5

These suppositories use a full-spectrum hemp extract and various essential oils. Unfortunately, Palmetto Harmony doesn’t list the exact ingredients of this formula — leaving us guessing as to the exact formula of this product. 

We can’t provide a high rating for this product without knowing the other ingredients used in the formula. 

Palmetto Harmony CBD Suppositories

Article By
Editorial Staff , last updated on November 16, 2021

CBD suppositories have a very specific set of applications — but can be very hard to find on the market these days. There are only a few companies that sell CBD suppositories, and even fewer that sell CBD suppositories we’d consider high-quality.

Most CBD suppositories we’ve reviewed don’t survive the mail intact — often melting during transport.

But these suppositories are different.

Palmetto Harmony has put together a great CBD product for its loyal customers here, with a low dose of 10 milligrams per suppository — making them more suitable for minor symptoms, or people sensitive to the effects of CBD. We also found these supplements were able to resist the normal environmental heat during transport — arriving safely in the mail as planned.

In this review, we’ll take a look at Palmetto Harmony CBD suppositories to compare how they stack up to the competition. We cover the dose, cost, and uses of these unique CBD products.

Overview: Palmetto Harmony Spectrum Suppositories

Janel Ralph started Palmetto Harmony in 2015 after looking for natural and organic ways to manage her daughter’s seizures. She had tried several pharmaceuticals in the past — with limited success.

Janel turned to CBD after hearing that about its potential to prevent and reduce the severity of seizures. It was a huge improvement compared with other treatments and reduced her daughter’s seizures by about 90%.

After this success, Janel made it her mission to provide the highest-quality organic CBD extracts on the market.

This mission has resulted in Palmetto Harmony’s decent range of products, which includes tinctures, vape oils, topicals, pet products, oral capsules, and suppositories.

Suppositories are a rarity in the CBD industry, so it’s good to see Palmetto Harmony providing an option for people who may need this niche form of CBD application.

Palmetto Harmony CBD suppositories are available in packs of seven — each containing 10 mg of full-spectrum CBD.

The suppositories are priced reasonably at $19.99 per pack.

Pros & Cons

Pros Cons
  • Extensive third-party lab test results
  • Option for people who cannot use other methods of CBD consumption
  • Inexpensive suppository option
  • Low potency for a CBD suppository
  • Other ingredients not listed

Key Features & Benefits

1. Extensive Third-Party Lab Test Results

Benefit: Know exactly what you’re putting into your body.

Many people use CBD as a daily health supplement. As such, it’s important to know that the CBD has been made with high-quality ingredients and manufacturing processes.

Palmetto Harmony provides detailed third-party lab test results for all of its CBD extracts. Each batch is tested for cannabinoid content, terpenes, heavy metals, pesticides, solvents, microbes, mold, and more. Therefore, if you want to be sure of the quality, Palmetto Harmony is a great choice.

2. CBD Option for People Who Cannot Use Other Methods

Benefit: Opens the door to CBD for people who otherwise would be unable to use it.

For people who have limited mobility, difficulty swallowing, digestive issues, or other health problems that make it hard to use CBD, suppositories can be the perfect solution.

As an added benefit, suppositories tend to allow more of the CBD content to pass into your bloodstream. This means that you may require less product to achieve similar results compared with capsules, tinctures, or vape oils.

3. Inexpensive Suppository

Benefit: Spend less on your CBD.

CBD suppositories can get quite expensive. It’s not unusual to see them sold for $0.50 per mg of CBD.

At just $0.28 per mg of CBD, Palmetto Harmony CBD suppositories are priced to sell. This is especially true because they’re made with high-quality, full-spectrum CBD.

4. Delivers CBD Directly to the Lower Digestive Tract

Benefit: Provide high doses of CBD to the affected area.

The main use of CBD suppositories is to provide a relatively high dose of CBD to inflamed or irritated sections of the lower digestive tract. By using suppositories, you’re able to bypass the digestive process to ensure as much of the CBD comes into contact with the affected area as possible.

Likewise, CBD suppositories are great for use with vaginal discomfort as well — again, delivering relatively high doses of CBD directly to the site.

About the Company: Palmetto Harmony

Palmetto Harmony was started by a concerned mother looking for a way to naturally manager her daughter’s seizures. She had limited success with traditional medicines — with the help of CBD, she claims that her daughter’s seizures were reduced by as much as 90%.

After seeing the difference CBD made in her daughter’s life, Palmetto Harmony has made its mission to provide families with high-quality CBD products at reasonable prices.

The company has since expanded its product line to include tinctures, capsules, topicals, suppositories pet products, and vape oils.

How Should Consider Using Palmetto Harmony Suppositories?

Customers who are unable to take other CBD products (tinctures, capsules, vape oils) may want to consider CBD suppositories. Suppositories are fast-acting and tend to last longer than many other delivery methods — which makes them an attractive option for people with more unexpected or sudden symptoms.

Palmetto Harmony Suppositories contain 10 mg of CBD each. The company states that they may support healthy inflammatory responses.


Many of Palmetto Harmony’s other products are more expensive than the market average.

However, this isn’t the case with its suppositories. At only $0.28 per mg of CBD, Palmetto Harmony’s full-spectrum, third-party tested CBD suppositories are a great deal. Most other CBD suppositories cost around $0.50 per mg of CBD used in the formula — making these about 40% cheaper than the industry average.

Palmetto Harmony CBD Suppositories Cost Breakdown

Product Name CBD per Suppository Total CBD Total Price Price Per mg CBD
Palmetto Harmony Spectrum Suppositories 10 mg 70 mg $19.99 $0.28

CBD Potency

Each suppository contains 10 mg of CBD, which is on the lower end of the potency spectrum. As a specialty product, we would like to see a slightly more potent option as well, for those with high daily CBD requirements.

However, 10 mg suppositories are still more potent on the lower digestive tract and vaginal cavity compared to oral CBD applications — as all the CBD in the suppository reaches the affected tissue, rather than being distributed around the body via the bloodstream.

We’d really like to see a stronger product option — as most other CBD suppositories offer closer to 50 or even 100 mg of CBD per suppository.

Hemp Source

As of May 2019, Palmetto Harmony became the first vertically integrated CBD company to be USDA Certified Organic – the company announcement states:

The Palmetto Harmony grow, manufacturing and product line is now all Certified Organic through the USDA. Soil fertility and crop nutrients are managed through tillage and cultivation practices, crop rotations and cover crops.  It is also supplemented with worm castings which introduce uncountable numbers of beneficial microbes and bacteria into the soil, aid in plant nutrient absorption and act as a super food for our plants. Our crop pests, weeds, and diseases are controlled primarily through management practices including physical, mechanical, and biological controls such as ladybugs, pirate bugs and praying mantes. Nematodes are used within the soil system to enhance nutrient mineralization as well as to act as biological control agents. The use of genetic engineering, or genetically modified organisms (GMOs), is prohibited in organic products.

This is huge news for both Palmetto Harmony and the CBD industry in general.

A USDA organic stamp of approval not only showcases the company’s determination to provide the highest quality products using stringent growing and manufacturing practices, but it also paves the way for other CBD companies.

All of the extracts are full-spectrum and, therefore, contain a wide range of cannabinoids and terpenes. Palmetto Harmony provides third-party lab test results upon request to provide reassurance of quality and absence of contaminants.

We’d love to see a batch system developed so customers can check the test results for the specific product they’re holding in their hands – this practice is quickly becoming the standard for the industry.


Suppositories are very specialized in their uses. These products are meant to provide a high dose of active CBD and other soothing agents like waxes, oils, and anti-inflammatories to the colon or vaginal cavity.

This highly specialized product scores full points in this category — but would be even better if the company used a higher dosage of CBD, and included other ingredients that supplemented the effects of the active cannabinoids.

It’s rare to find CBD suppositories that include other beneficial herbs or supplements, so we can’t be too hard on Palmetto Harmony for this.

Because anal and intravaginal application of CBD is relatively uncommon – though it is picking up steam now that more CBD companies are producing them – there seems to be a lack of research that verifies the actual bioavailability of cannabinoids, especially ones that aren’t synthetic.

Product Variations

Palmetto Harmony only sells one type of CBD suppository, which makes sense. As a specialty product, we don’t expect companies to offer more than one or two options.

As we’ve already mentioned, we’d really like to see a stronger version of these suppositories offered by Palmetto Harmony as we feel the 10 mg dose is insufficient for more severe symptoms. Most people using suppositories have already tried other forms of CBD and are looking for something that’s going to offer the highest dose possible.

With that said, we still like the 10 mg option for people who are more sensitive to CBD. Even though this form of CBD is the best way to keep CBD locally, it will also absorb through the mucous membranes and rectal capillaries. Using CBD suppositories will increase blood levels of CBD and exert effects elsewhere in the body.

Final Verdict: Excellent CBD Suppository at a Good Price

If you’re interested in CBD suppositories, Palmetto Harmony is the way to go. They’re made with high-quality US hemp and priced significantly lower than many other options on the market.

The dose is on the lower side of the potency spectrum, but remember that rectal tissue is highly effective at absorbing CBD. Therefore, even though it’s a lower potency, a higher percentage of CBD will make it into your bloodstream compared with tinctures, oral capsules, gummies, or topicals.

Ideally, Palmetto Harmony would offer a choice between these low dose CBD suppositories, and a higher potency option closer to 50 mg per unit.

If you’re looking for an affordable CBD suppository for rectal OR vaginal use, we recommend this product.

Similar Products:

Number Product Total CBD Potency Cost per mg CBD Link


Foria Suppositories

880 mg

110 mg/suppository



Endoca CBD Suppositories

500 mg

50 mg/suppository

0.09 €


CBDistillery CBD Suppositories

150 mg

50 mg/suppository


Palmetto Harmony

4.83 / 5