Best CBD:THC Ratio for Anxiety

Benefits of CBD & THC For Anxiety

CBD and THC have both been widely studied as treatments for anxiety and related illnesses.

Whether you take them together or separately, CBD and THC may provide anxiety relief as well as relief for anxiety-related symptoms, specifically poor sleep, nausea, and loss of appetite.

CBD may work for anxiety in a few different ways. For instance, CBD modulates DNA methylation in the prefrontal cortex — one of the potential causes of anxiety [1].

CBD interacts with the GABA receptors, which are responsible for the body’s experience of stress or anxiety. GABA activity promotes feelings of calm, and cannabinoids promote that activity.

THC and CBD also interact with the CB1 and CB2 receptors to both inhibit stress response and lower the psychoactive effects of CBD when taken together [2]. Both cannabinoids work to calm the muscles and nerves, offering physical relaxation for anxiety sufferers who find themselves clenching their teeth or tensing their muscles.

Some people with anxiety experience poor sleep, trouble falling asleep, or disruptive nightmares. CBD and THC may lower the experience of anxiety while sleeping and can also make it easier to get to sleep (and stay asleep through the night) [3].

THC may also work to boost appetite, which can be helpful for anxiety sufferers who lose interest in food when they’re feeling anxious.

The Benefits of THC and CBD For Anxiety Include: 

• Lessened anxiety symptoms
• Relaxed muscles
• Lowered inflammation in the brain
• Improved sleep
• Boosted appetite
• Lowered psychological effects of THC

Will CBD & THC Interact With My Anxiety Medications? 

Anxiety is often treated with medications that interact with serotonin and norepinephrine receptors. 

CBD and THC also provide an increase in serotonin levels, but it’s important to make sure you don’t have too much serotonin. 

Make sure to always ask your doctor about interactions with any other medications you take to treat your anxiety, especially antidepressants.

CBD & THC Ratio for Anxiety: What Dose Should I Take?

The best CBD:THC ratio for anxiety is 1:1, meaning equal parts CBD and THC.

If you feel anxious after taking THC on its own, pairing it with CBD can help reduce the psychoactive impacts of THC. A ratio higher in CBD may be better for anxiety patients who want the relaxation of weed while also enjoying the benefits of CBD.

Our simple CBD dosage calculator is a great way to figure out your ideal dose after determining the ratio you want. 

CBD and THC gummies and oils can be used for ratios because you can easily cut the gummies or measure the oil. You can also buy CBD:THC ratio products that are already mixed for you at dispensaries or online.

Other CBD:THC Ratios

The best ratio of CBD to THC is a hot topic lately. While we already have a lot of data available for the benefits of both these cannabinoids for certain conditions — there’s very little information about what the optimal ratio of each one is when used in conjunction.

As more research comes to light on the intricate synergy between these two compounds, scientists are uncovering insight into ways we can get even more effectiveness out of cannabis.

Here are some of the other optimal CBD to THC ratios based on the current evidence so far:

• Best CBD:THC Ratio for Multiple Sclerosis — 1:1
• Best CBD:THC Ratio for Pain — 1:10
• Best CBD:THC Ratio for Arthritis — 1:1
• Best CBD:THC Ratio for Neuropathy — 1:1
• Best CBD:THC Ratio for Fibromyalgia — 1:1, 2:1, or 3:1

Final Thoughts: Best CBD:THC Ratio For Anxiety

The best CBD:THC ratio for anxiety is 1:1, with equal or more parts CBD to every one part THC. 

Both THC and CBD can help manage anxiety and its uncomfortable symptoms. Used together, you can harness the power of both compounds, increase their efficacy, and lessen the psychological effects of THC.

Pharmaceutical medications that include both CBD and THC are easily accessible if you’re a medical marijuana patient. Otherwise, you can find these ratio products at your local dispensary or make your own by measuring your CBD and THC doses at home.

References

1. Sales, A. J., Guimarães, F. S., & Joca, S. R. (2020). CBD modulates DNA methylation in the prefrontal cortex and hippocampus of mice exposed to forced swim. Behavioural brain research, 388, 112627.
2. Boggs, D. L., Nguyen, J. D., Morgenson, D., Taffe, M. A., & Ranganathan, M. (2018). Clinical and preclinical evidence for functional interactions of cannabidiol and Δ 9-tetrahydrocannabinol. Neuropsychopharmacology, 43(1), 142-154.
3. Lafaye, G., Karila, L., Blecha, L., & Benyamina, A. (2017). Cannabis, cannabinoids, and health. Dialogues in clinical neuroscience, 19(3), 309.