{"id":33831,"date":"2021-10-15T01:03:19","date_gmt":"2021-10-15T01:03:19","guid":{"rendered":"https:\/\/dailycbd.cc\/en\/?p=33831"},"modified":"2021-11-23T21:10:12","modified_gmt":"2021-11-23T21:10:12","slug":"ratio-neuropathy","status":"publish","type":"post","link":"https:\/\/dailycbd.com\/en\/ratios\/neuropathy\/","title":{"rendered":"Best CBD:THC Ratio For Neuropathy"},"content":{"rendered":"\n<h2>What is Neuropathy? What Causes It?&nbsp;<\/h2>\n\n\n\n<p>Neuropathy refers to nerve pinching, compression, and damage resulting in pain.&nbsp;<\/p>\n\n\n\n<p>There are many different causes of neuropathy, ranging from traumatic injuries to degenerative disorders like <a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/multiple-sclerosis\/\">multiple sclerosis<\/a> or <a href=\"http:\/\/dailycbd.com\/en\/cerebral-palsy\/\">cerebral palsy<\/a>.&nbsp;<\/p>\n\n\n\n<p>The condition leaves patients with significant pain, numbness, and, in severe cases, a reduction in autonomy and paralysis.<\/p>\n\n\n\n<p>Neuropathic pain is especially difficult to treat. Conventional painkillers like acetaminophen don&#8217;t normally work that well for this type of pain because they target inflammation. Because the pain originates from the neurons themselves, reducing inflammation has little impact on pain.&nbsp;<\/p>\n\n\n\n<h2>Benefits of CBD &amp; THC For Neuropathy<\/h2>\n\n\n\n<p>CBD has been widely studied for addressing neuropathy or nerve pain.&nbsp;<\/p>\n\n\n\n<p>CBD on its own may be helpful for peripheral neuropathy, with patients reporting less pain after taking CBD.&nbsp;<\/p>\n\n\n\n<p>CBD has been observed to reduce inflammation in neuropathy patients by interacting with the \u03b1<sub>3<\/sub>-glycine receptors, which are responsible for our sense of pain [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7204604\/\">1<\/a>].<\/p>\n\n\n\n<p><strong>The Benefits of THC and CBD For Neuropathy Include:&nbsp;<\/strong><\/p>\n\n\n\n<ul><li>Reducing inflammation<\/li><li>Managing chronic pain<\/li><li>Relieving symptoms of depression<\/li><li>Supporting healthy sleep quality<\/li><li>Promoting nerve regeneration<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image size-full\"><img width=\"612\" height=\"408\" src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/neuropathy-1.png\" alt=\"\" class=\"wp-image-33833\" srcset=\"https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/neuropathy-1.png 612w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/neuropathy-1-300x200.png 300w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/neuropathy-1-180x120.png 180w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/neuropathy-1-283x189.png 283w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/neuropathy-1-54x36.png 54w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/neuropathy-1-330x220.png 330w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/neuropathy-1-420x280.png 420w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/neuropathy-1-74x49.png 74w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/neuropathy-1-45x30.png 45w\" sizes=\"(max-width: 612px) 100vw, 612px\" \/><\/figure>\n\n\n\n<h2>Will CBD &amp; THC Interact With My Neuropathy Medications?&nbsp;<\/h2>\n\n\n\n<p>Neuropathy is often treated with prescription medications \u2014 many of which may interact negatively with CBD.&nbsp;<\/p>\n\n\n\n<p>Make sure to always ask your doctor about <a href=\"http:\/\/dailycbd.com\/en\/drug-interactions\/\">interactions with any other medications<\/a> you take to treat your neuropathy, especially antidepressants.<\/p>\n\n\n\n<p>Common neuropathy medications and their potential interaction with CBD:&nbsp;<\/p>\n\n\n\n<h3>1. Opiate Painkillers<\/h3>\n\n\n\n<p>Opiates are commonly used to treat nerve pain. They&#8217;re considered to be one of the strongest classes of prescription painkillers available. They work by targeting the opiate receptors in the central nervous system. This effect blocks the transmission of pain heading from the body to the brain.&nbsp;<\/p>\n\n\n\n<p><a href=\"http:\/\/dailycbd.com\/en\/drug-interactions\/#h3-opiate-painkillers-cbd-1\">CBD may interact with opioid pain medications<\/a>. This supplement has a similar effect as opiates on inhibiting neurological function and may compete for metabolism in the liver. Both of these effects could lead to an increased risk of side effects and overdose.&nbsp;<\/p>\n\n\n\n<p>Always speak to your doctor about using CBD if you\u2019ve been prescribed an opioid medication.&nbsp;<\/p>\n\n\n\n<p><strong>Common opiates used for neuropathic pain include:&nbsp;<\/strong><\/p>\n\n\n\n<ul><li>Buprenorphine (Cizdol &amp; Brixadi)<\/li><li>Codeine<\/li><li>Pethidine (Meperidine &amp; Demerol)<\/li><li>Fentanyl (Abstral &amp; Actiq)<\/li><li>Hydrocodone (Hysingla ER, Zohydro ER &amp; Hycodan)<\/li><li>Hydromorphone (Dilaudid)<\/li><li>Methadone (Methadose &amp; Dolophine)<\/li><li>Morphine (Kadian &amp; Roxanol)<\/li><li><a href=\"http:\/\/dailycbd.com\/en\/drug-interactions\/oxycodone\/\">Oxycodone<\/a> (Percodan, Endodan, Roxiprin, Percocet, Endocet, Roxicet &amp; OxyContin)<\/li><li><a href=\"http:\/\/dailycbd.com\/en\/drug-interactions\/tramadol\/\">Tramadol<\/a> (Ultram, Ryzolt &amp; ConZip)<\/li><\/ul>\n\n\n\n<h3>2. Antidepressants<\/h3>\n\n\n\n<p>Long-term neuropathic pain often leads to depression. Lowered quality of life, poor sleep, and job loss all contribute further to this effect.&nbsp;<\/p>\n\n\n\n<p>If you\u2019ve been prescribed antidepressants, it\u2019s important to speak with your prescribing doctor about CBD and THC first. Both compounds can interfere with the metabolism of drugs like <a href=\"http:\/\/dailycbd.com\/en\/drug-interactions\/#h3-ssri-medications-cbd-1\">SSRIs<\/a> and <a href=\"http:\/\/dailycbd.com\/en\/drug-interactions\/#h3-snri-medications-cbd-2\">SNRIs<\/a> and lead to negative side effects.&nbsp;<\/p>\n\n\n\n<p>THC is especially likely to interact with these substances in a negative way.&nbsp;<\/p>\n\n\n\n<p><strong>Common prescription antidepressants include:&nbsp;<\/strong><\/p>\n\n\n\n<ul><li>Citalopram (Cipramil &amp; Celexa)<\/li><li>Dapoxetine (Priligy)<\/li><li>Escitalopram (Cipralex &amp; Lexapro)<\/li><li>Fluoxetine (Prozac, Rapiflux, Sarafem, Selfemra &amp; Oxactin)<\/li><li>Fluvoxamine (Faverin)<\/li><li>Paroxetine (Seroxat)<\/li><li><a href=\"http:\/\/dailycbd.com\/en\/drug-interactions\/sertraline\/\">Sertraline<\/a> (Lustral)<\/li><li>Vortioxetine (Brintellix)<\/li><li>Atomoxetine (Strattera)<\/li><li>Desvenlafaxine (Pristiq, Khedezla)<\/li><li>Duloxetine (Cymbalta, Irenka)<\/li><li>Levomilnacipran (Fetzima)<\/li><li>Milnacipran (Savella)<\/li><li>Venlafaxine (Effexor XR)<\/li><\/ul>\n\n\n\n<h2>CBD &amp; THC Ratios: What Dose Should I Take?<\/h2>\n\n\n\n<p>The best CBD:THC ratio for neuropathy is 1:1+, meaning equal parts CBD and THC <em>or<\/em> less CBD than THC.<\/p>\n\n\n\n<p><strong>Keep in mind that dosing and ratio are two very different things.&nbsp;<\/strong><\/p>\n\n\n\n<p>The dose refers to how much of the compounds you&#8217;re taking, and it&#8217;s typically measured in milligrams. There is no one-size-fits-all approach to dosing for neuropathic pain, but higher doses (50 mg +) have been shown to provide the most relief towards pain and inflammation.&nbsp;<\/p>\n\n\n\n<p>To determine your doses, you can try our <a href=\"http:\/\/dailycbd.com\/en\/cbd-dosage\/\">dosage calculator<\/a>. This will give you a rough estimate of how much CBD you should consume depending on your weight and desired strength, but you can expect to experiment with your doses as cannabinoids affect individuals differently.&nbsp;<\/p>\n\n\n\n<p>CBD and THC gummies and oils are easy to dose using ratios because you can cut the gummies or measure oil in mL. However, you can also buy CBD:THC ratio products that are already mixed for you.<\/p>\n\n\n\n<h2 id=\"h2-other-cbdthc-ratios-2\">Other CBD:THC Ratios<\/h2>\n\n\n\n<p><a href=\"https:\/\/dailycbd.com\/en\/ratios\/\">The best ratio of CBD to THC<\/a>&nbsp;is a hot topic lately. While we already have a lot of data available for the benefits of both these cannabinoids for certain conditions \u2014 there\u2019s very little information about what the optimal ratio of each one is when used in conjunction.<\/p>\n\n\n\n<p>As more research comes to light on the intricate synergy between these two compounds, scientists are uncovering insight into ways we can get even more effectiveness out of cannabis.<\/p>\n\n\n\n<p><strong>Here are some of the other optimal CBD to THC ratios based on the current evidence so far:<\/strong><\/p>\n\n\n\n<ul><li><a href=\"https:\/\/dailycbd.com\/en\/ratios\/multiple-sclerosis\/\"><strong>Best CBD:THC Ratio for Multiple Sclerosis<\/strong><\/a><strong>\u00a0\u2014\u00a0<\/strong>1:1<\/li><li><a href=\"https:\/\/dailycbd.com\/en\/ratios\/pain\/\"><strong>Best CBD:THC Ratio for Pain<\/strong><\/a><strong>\u00a0\u2014\u00a0<\/strong>1:10<\/li><li><strong><a href=\"https:\/\/dailycbd.com\/en\/ratios\/arthritis\/\">Best CBD:THC Ratio for Arthritis<\/a><\/strong> <strong>\u2014 <\/strong>1:1<\/li><li><strong><a href=\"https:\/\/dailycbd.com\/en\/ratios\/fibromyalgia\/\">Best CBD:THC Ratio for Fibromyalgia<\/a><\/strong> \u2014 1:1, 2:1, or 3:1<\/li><li><strong><a href=\"https:\/\/dailycbd.com\/en\/ratios\/anxiety\/\">Best CBD:THC Ratio for Anxiety<\/a> \u2014<\/strong> 1:1<\/li><\/ul>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img width=\"612\" height=\"408\" src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/plant-cbd-oil.png\" alt=\"\" class=\"wp-image-33834\" srcset=\"https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/plant-cbd-oil.png 612w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/plant-cbd-oil-300x200.png 300w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/plant-cbd-oil-180x120.png 180w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/plant-cbd-oil-283x189.png 283w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/plant-cbd-oil-54x36.png 54w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/plant-cbd-oil-330x220.png 330w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/plant-cbd-oil-420x280.png 420w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/plant-cbd-oil-74x49.png 74w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/plant-cbd-oil-45x30.png 45w\" sizes=\"(max-width: 612px) 100vw, 612px\" \/><\/figure><\/div>\n\n\n\n<h2><strong>Final Thoughts: Best CBD:THC Ratio For Neuropathy<\/strong><\/h2>\n\n\n\n<p>The best CBD:THC ratio for neuropathy is 1:1 with equal parts THC to CBD.&nbsp;<\/p>\n\n\n\n<p>Both THC and CBD are useful in managing pain from this condition. Taken together, the effects become even stronger.&nbsp;<\/p>\n\n\n\n<p>There are several pharmaceutical medications using CBD and THC for treating pain \u2014 the majority of which use this same 1:1 ratio.&nbsp;<\/p>\n\n\n\n<p>You can achieve this ratio by taking equal doses of CBD oil and THC oil or by mixing roughly equivalent doses of CBD or THC vape pens, capsules, gummies, or other products. You don\u2019t have to use a premade CBD:THC product to get the benefits of this combination.&nbsp;<\/p>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<h2>References<\/h2>\n\n\n\n<ol><li>Argueta, D. A., Ventura, C. M., Kiven, S., Sagi, V., &amp; Gupta, K. (2020). A balanced approach for cannabidiol use in chronic pain. Frontiers in pharmacology, 11, 561.<\/li><li>Berman, J. S., Symonds, C., &amp; Birch, R. (2004). Efficacy of two cannabis-based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomized controlled trial. Pain, 112(3), 299-306.<\/li><li>Boggs, D. L., Nguyen, J. D., Morgenson, D., Taffe, M. A., &amp; Ranganathan, M. (2018). Clinical and preclinical evidence for functional interactions of cannabidiol and \u0394 9-tetrahydrocannabinol. Neuropsychopharmacology, 43(1), 142-154.<\/li><li>Ware, M. A., Wang, T., Shapiro, S., Robinson, A., Ducruet, T., Huynh, T., &#8230; &amp; Collet, J. P. (2010). Smoked cannabis for chronic neuropathic pain: a randomized controlled trial. Cmaj, 182(14), E694-E701.<\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Sometimes two is better than one. <\/p>\n<p>Learn how to use CBD &amp; THC together for neuropathy and which ratio is best. <\/p>\n","protected":false},"author":1,"featured_media":34008,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[30,925,3564,3571,3574],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Best CBD:THC Ratio For Neuropathy<\/title>\n<meta name=\"description\" content=\"The combination of CBD and THC is a powerful treatment for nerve damage and neuropathic pain. 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