{"id":33708,"date":"2021-10-14T14:47:08","date_gmt":"2021-10-14T14:47:08","guid":{"rendered":"https:\/\/dailycbd.cc\/en\/?page_id=33708"},"modified":"2021-10-21T21:33:22","modified_gmt":"2021-10-21T21:33:22","slug":"ivermectin","status":"publish","type":"page","link":"https:\/\/dailycbd.com\/en\/drug-interactions\/ivermectin\/","title":{"rendered":"Does CBD Interact With Ivermectin (Stromectol)?"},"content":{"rendered":"\n<h2>Does CBD Interact With Ivermectin (Stromectol)?<\/h2>\n\n\n\n<p>CBD may slow the breakdown and elimination of ivermectin (Stromectol) by competing for similar metabolic pathways in the liver.<\/p>\n\n\n\n<p>However, the level of risk with this interaction is minimal, and no major side effects have been reported from this combination.<\/p>\n\n\n\n<p>CBD works by acting on the <a href=\"http:\/\/dailycbd.com\/en\/endocannabinoid-system\/\">endocannabinoid system (ECS)<\/a>. It mainly works on the CB2 and serotonin 5-HT1A receptors. CBD&#8217;s exact mechanism of action on parasites has not been determined yet. On the other hand, ivermectin works by binding to the glutamate-gated chloride channels of the organisms and causing their death.<\/p>\n\n\n\n<h2><a><\/a>Other Names for Ivermectin<\/h2>\n\n\n\n<p>Ivermectin is sold under many different names. All share the same risk and potential interactions.<\/p>\n\n\n\n<p><strong>Other names for ivermectin include:<\/strong><\/p>\n\n\n\n<ul><li>Stromectol<\/li><li>Soolantra<\/li><li>Sklice<\/li><\/ul>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img width=\"500\" height=\"500\" src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra.png\" alt=\"\" class=\"wp-image-33710\" srcset=\"https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra.png 500w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-300x300.png 300w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-150x150.png 150w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-180x180.png 180w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-158x158.png 158w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-80x80.png 80w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-120x120.png 120w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-70x70.png 70w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-40x40.png 40w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-283x283.png 283w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-54x54.png 54w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-330x330.png 330w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-420x420.png 420w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-74x74.png 74w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/soolantra-30x30.png 30w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/figure><\/div>\n\n\n\n<h2><a><\/a>Similar Medications: CBD &amp; Avermectins<\/h2>\n\n\n\n<p>Ivermectin is classified as an avermectin. <a href=\"http:\/\/dailycbd.com\/en\/drug-interactions\/#h2-cbd-antimicrobials-16\">CBD and avermectins<\/a> all share similar risks for interaction and side effects.<\/p>\n\n\n\n<p><strong>Here&#8217;s a list of similar medications that share a similar level of risk when combined with CBD:<\/strong><\/p>\n\n\n\n<ul><li>Selamectin<\/li><li>Doramectin<\/li><li>Eprinomectin<\/li><li>Abamectin<\/li><\/ul>\n\n\n\n<h2><a><\/a>Is It Safe to Take CBD &amp; Ivermectin (Stromectol) Together?<\/h2>\n\n\n\n<p>The safety of using CBD and ivermectin together is not well studied \u2014 however, no significant side effects are expected.<\/p>\n\n\n\n<p>If you want to take CBD and ivermectin together, <a href=\"http:\/\/dailycbd.com\/en\/talk-to-your-doctor-cbd\/\">consult your doctor first<\/a>, get yourself assessed, and then follow their suggestions.<\/p>\n\n\n\n<p>To lessen the chances of interaction, the best way to take these drugs is to finish the complete course of one medication first and then start the other one \u2014 rather than using both simultaneously.<\/p>\n\n\n\n<p>Always speak to your doctor about CBD first if you\u2019re taking ivermectin for any reason.<\/p>\n\n\n\n<h2><a><\/a>Is CBD a Viable Alternative to Ivermectin (Stromectol)?<\/h2>\n\n\n\n<p>CBD and ivermectin are entirely different substances. CBD is not considered a viable alternative to ivermectin for the purpose of eliminating parasitic worms.<\/p>\n\n\n\n<p>Cannabis has a long history of being used as a traditional antiparasitic medication in some parts of India and Uganda.<\/p>\n\n\n\n<p><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/inflammation\/\">CBD may also help to lower the inflammation<\/a> caused by these parasites, but there are no indications CBD possesses direct antiparasitic effects.<\/p>\n\n\n\n<h2><a><\/a>What Is Ivermectin (Stromectol)?<\/h2>\n\n\n\n<p>Ivermectin (Stromectol) is a medication used to treat parasite infections. It belongs to the avermectin group of drugs.<\/p>\n\n\n\n<p>It also treats diseases like head lice, scabies, river blindness, onchocerciasis, strongyloidiasis, trichuriasis, ascariasis, and lymphatic filariasis.<\/p>\n\n\n\n<p>Ivermectin is usually taken as an oral pill but is also applied for some conditions like rosacea.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-medium\"><img width=\"300\" height=\"300\" src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-300x300.png\" alt=\"\" class=\"wp-image-33561\" srcset=\"https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-300x300.png 300w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-150x150.png 150w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-768x768.png 768w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-180x180.png 180w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-158x158.png 158w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-80x80.png 80w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-120x120.png 120w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-70x70.png 70w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-40x40.png 40w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-283x283.png 283w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-54x54.png 54w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-330x330.png 330w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-420x420.png 420w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-74x74.png 74w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1-30x30.png 30w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/10\/ivermectin-molecule1.png 800w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/figure><\/div>\n\n\n\n<h3><a><\/a>Ivermectin Specs:<strong><\/strong><\/h3>\n\n\n\n<div class=\"t-old\"><figure class=\"wp-block-table\"><table><tbody><tr><td>Drug Name<\/td><td>Ivermectin <strong>&nbsp;<\/strong><\/td><\/tr><tr><td>Trade Name<\/td><td>Stromectol, Agimect, Escapil, Soolantra, Sklice <strong>&nbsp;<\/strong><\/td><\/tr><tr><td>Other Names (other generics)<\/td><td>22,23-dihydroavermectin<\/td><\/tr><tr><td>CYP Metabolism<\/td><td>CYP3A4 (minimal)<\/td><\/tr><tr><td>Interaction With CBD<\/td><td>Metabolic competition<\/td><\/tr><tr><td>Risk of Interaction<\/td><td>Mild <strong>&nbsp;<\/strong><\/td><\/tr><\/tbody><\/table><\/figure><\/div>\n\n\n\n<h2><a><\/a>What Does Ivermectin (Stromectol) Do?<\/h2>\n\n\n\n<p>Ivermectin (Stromectol) works by hindering the nerve and the muscle functions of parasitic worms. This drug has an attraction to the glutamate-gated chloride ion channels in the bodies of these parasites. This binding action causes an increase in the permeability of the cell membranes, causing an easy flow of chloride ions.<\/p>\n\n\n\n<p>This causes hyperpolarization in the cell body of the parasites. It then leads to the paralysis of the parasite and, eventually, death. It is safe for use in mammals as the blood-brain barrier prevents the entry of ivermectin into the nervous system, as long as it&#8217;s in low doses.<\/p>\n\n\n\n<p>Ivermectin may also impair the normal intrauterine development of the microfilariae of Onchocerca volvulus. It may inhibit their birth and lead to the death of these organisms. It is a very effective antiparasitic drug.<\/p>\n\n\n\n<h3><a><\/a>Side Effects of Ivermectin<\/h3>\n\n\n\n<ul><li>Abdominal pain<\/li><li>Asthenia<\/li><li>Blurred vision<\/li><li>Conjunctival hemorrhage (with onchocerciasis)<\/li><li>Diarrhea<\/li><li>Dizziness<\/li><li>Eosinophilia<\/li><li>Eye damage<\/li><li>Fever<\/li><li>Headache<\/li><li>Hepatitis<\/li><li>Hyperthermia<\/li><li>Hypotension<\/li><li>Insomnia<\/li><li>Leukopenia<\/li><li>Liver enzyme dysfunction<\/li><li>Lymphadenopathy<\/li><li>Mazzotti reaction (with onchocerciasis)<\/li><li>Mild conjunctivitis<\/li><li>Nausea<\/li><li>Peripheral and facial edema<\/li><li>Pruritus<\/li><li>Rash<\/li><li>Sleepiness<\/li><li>Transient tachycardia<\/li><li>Tremor<\/li><li>Urticaria<\/li><li>Vertigo<\/li><li>Vomiting<\/li><li>Weakness<\/li><\/ul>\n\n\n\n<h2><a><\/a>Types of Drug Interactions With CBD<\/h2>\n\n\n\n<p><a href=\"http:\/\/dailycbd.com\/en\/cbd-oil-benefits\/\">CBD may alleviate many conditions<\/a>; however, like most medically relevant substances, CBD&#8217;s chemical nature makes it liable to interact with many other drugs.<\/p>\n\n\n\n<p>There are three ways that CBD can interact with other drugs:<\/p>\n\n\n\n<h3><a><\/a>1. Agonistic Interaction<\/h3>\n\n\n\n<p>This interaction can occur due to the medicines that have the <strong>same <\/strong>effect on the body. They work on the same receptors on the body leading to effects in the same direction.<\/p>\n\n\n\n<p><strong>Examples of medications that could cause agonistic interaction with CBD are:<\/strong><\/p>\n\n\n\n<ul><li><strong>Antihypertensive Medications <\/strong>\u2014 These include beta-blockers, central agonists, diuretics, ACE inhibitors, alpha-blockers, calcium channel blockers, and angiotensin II receptor blockers. CBD can cause low blood pressure if taken alongside these medications.<\/li><li><strong>Antidiabetic medications<\/strong> \u2014 These include SGLT-2 inhibitors, sulfonylureas, and insulin, alpha-glucosidase inhibitors, GLP-1 receptor agonists, meglitinides, and DPP-4 inhibitors. CBD could decrease blood sugar beyond normal if used with these medications.<\/li><li><strong>Anti-anxiety medications <\/strong>\u2014 These include drugs like benzodiazepines and barbiturates. CBD could make them last longer in the body.<\/li><\/ul>\n\n\n\n<h3><a><\/a>2. Antagonistic Interaction<\/h3>\n\n\n\n<p>This is the <strong>opposite<\/strong> of the agonistic interaction. It happens when two drugs have effects opposite of each other. If taken together, one drug would cross out the effects of the other, causing a decreased efficacy of the second drug.<\/p>\n\n\n\n<p><strong>Drugs that have antagonistic interaction with CBD are:<\/strong><\/p>\n\n\n\n<ul><li><strong>Immunosuppressants <\/strong>\u2014 These include azathioprine, mycophenolate cyclosporine, methotrexate, etc. CBD&#8217;s immune-stimulating properties may cause these drugs to lose their efficiency.<\/li><li><strong>Stimulants<\/strong> \u2014 These include amphetamine, modafinil. CBD can cause them to be less productive.<\/li><li><strong>Immunomodulators<\/strong> \u2014 These include antihistamines like carbinoxamine, desloratadine, levocetirizine. CBD could enhance their sedative action.<\/li><li><strong>Asthma Medications <\/strong>\u2014 These include drugs like montelukast, ipratropium bromide, albuterol, fluticasone, and theophylline. CBD may limit their abilities, especially that of theophyllines.<\/li><\/ul>\n\n\n\n<h3><a><\/a>3. Metabolic Inhibition<\/h3>\n\n\n\n<p>Some medications need <strong>similar enzymes<\/strong> to break down the drug molecules. It leads to both drugs competing against each other, causing their metabolism to decrease.<\/p>\n\n\n\n<p><strong>These include medications like<\/strong><\/p>\n\n\n\n<ul><li><strong>Opiate analgesics <\/strong>\u2014 These include morphine, codeine, hydrocodone. CBD could make them last longer in the bloodstream and create complications.<\/li><li><strong>Antidepressants <\/strong>\u2014 CBD can make these drugs last longer in the body by diminishing their metabolism. Antidepressants include trazodone, mirtazapine, vortioxetine, and vilazodone, and others.<\/li><li><strong>Blood thinners <\/strong>\u2014 CBD could cause an increment in the action of warfarin, enoxaparin, heparin, and others that could be very unsafe.<\/li><li><strong>NSAIDs <\/strong><a href=\"http:\/\/dailycbd.com\/en\/drug-interactions\/aspirin\/\">\u2014 These include ibuprofen, naproxen, and high-dose aspirin<\/a>. CBD could make them last longer in the body, increasing their side effects.<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image size-large\"><img width=\"1024\" height=\"576\" src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-1024x576.jpg\" alt=\"Hemp farmer holding Cbd oil made of Cannabis sativa plant in a dropper and bottle.\" class=\"wp-image-27352\" srcset=\"https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-1024x576.jpg 1024w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-300x169.jpg 300w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-768x432.jpg 768w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-1536x864.jpg 1536w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-1920x1080.jpg 1920w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-180x101.jpg 180w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-283x159.jpg 283w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-54x30.jpg 54w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-330x186.jpg 330w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-420x236.jpg 420w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-74x42.jpg 74w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd-53x30.jpg 53w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2021\/01\/the-ecs-cbd.jpg 2000w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h2><a><\/a>Key Takeaways: Is It Safe to Take Ivermectin With CBD?<\/h2>\n\n\n\n<p>CBD and ivermectin (Stromectol) may interact with each other leading to their slow metabolism. This could cause them to last longer in the body and cause more damage.<\/p>\n\n\n\n<p>However, research regarding this is minimal. To prevent the chances of interaction, take these medications only under the strict supervision of your doctor.<\/p>\n\n\n\n<p>The best way to prevent any chances of interaction is to finish the duration of one drug dosage before starting the other. If you want to take both of them, it may be better to have adequate time intervals in between while taking both these medications.<\/p>\n\n\n\n<p>Do not overdose. If you get any side effects, contact your doctor immediately. Always stay on alert while taking these medications together.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Information on risks &amp; possible interactions between CBD &amp; ivermectin. <\/p>\n","protected":false},"author":19,"featured_media":33996,"parent":27451,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"categories":[3589],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Does CBD Interact With Ivermectin (Stromectol)?<\/title>\n<meta name=\"description\" content=\"Can CBD and ivermectin interact with each other? What are their effects? Can CBD replace ivermectin as an antiparasitic drug? 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