{"id":242,"date":"2020-09-28T08:28:00","date_gmt":"2020-09-28T08:28:00","guid":{"rendered":"http:\/\/dailycbd.com\/english\/?post_type=crb_condition&#038;p=242"},"modified":"2021-10-19T17:42:45","modified_gmt":"2021-10-19T17:42:45","slug":"inflammation","status":"publish","type":"crb_condition","link":"https:\/\/dailycbd.com\/en\/best-cbd\/inflammation\/","title":{"rendered":"Inflammation"},"content":{"rendered":"\n<h2>Best CBD Products For Inflammation<\/h2>\n\n\n\n<ul><li><strong>Best CBD Oil Overall \u2014<\/strong>\u00a0<a rel=\"noreferrer noopener nofollow\" href=\"\/en\/go\/royal-cbd\/cbd-oil-1000\" target=\"_blank\">Royal CBD Oil<\/a><\/li><li><strong>Best CBD Capsules \u2014<\/strong>\u00a0<a rel=\"noreferrer noopener nofollow\" href=\"\/en\/go\/goldbee\/cbd-capsules\" target=\"_blank\">Gold Bee CBD Capsules<\/a><\/li><li><strong>Best CBD Oil Formula<\/strong> \u2014 <a href=\"\/en\/go\/kiara-naturals\/pain-relief-tincture\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Kiara Naturals CBD Pain Relief Tincture<\/a><\/li><li><strong>Best Nano CBD Oil<\/strong> \u2014\u00a0<a rel=\"noreferrer noopener nofollow\" href=\"\/en\/go\/phoria\" target=\"_blank\">Phoria CBD Oil Nano Tincture<\/a><\/li><li><strong>Best CBD Oil in Europe<\/strong> \u2014\u00a0<a rel=\"noreferrer noopener nofollow\" href=\"\/en\/go\/nordic-oil\" target=\"_blank\">Nordic Oil Full-Spectrum CBD Oil<\/a><\/li><\/ul>\n\n\n\n<h2>Summary: Can CBD Help With Inflammation?<\/h2>\n\n\n\n<p>There are dozens of chemical messengers and enzymes working together to produce inflammation in the body.<\/p>\n\n\n\n<p>Blocking one pathway may prove useful for certain types of inflammation, but it\u2019s not the most effective method treatment.<\/p>\n\n\n\n<p>CBD is an excellent anti-inflammatory because it works through multiple pathways. By doing this, CBD halts the inflammatory process at several different points in the process.<\/p>\n\n\n\n<p>Compared with common anti-inflammatory drugs such as Aspirin \u2014 which inhibits only one enzyme involved in the inflammatory process \u2014 we find CBD more effective for combating inflammation.<\/p>\n\n\n\n<h2>What Type of CBD Products Should I Use? <\/h2>\n\n\n\n<p>CBD comes in all different forms \u2014 but not all are appropriate for every condition. When it comes to inflammation specifically, there are a few types of CBD that work better than others. <\/p>\n\n\n\n<p>Let&#8217;s cover the main types of CBD you&#8217;re likely to find and discuss their advantages and disadvantages for reducing inflammation. <\/p>\n\n\n\n<h3>1. CBD Oils &amp; Tinctures<\/h3>\n\n\n\n<p><a href=\"\/en\/products\/cbd-oil\/\">CBD oils<\/a> are the most common form of CBD that people are using today. They allow for simple, effective dosing, and have a long shelf-life. CBD tinctures are very similar to oils, but use alcohol as the carrier instead of oils. This gives them a longer shelf-life and it makes it easier for herbalists and naturopaths to mix other anti-inflammatory herbs into the formula&nbsp;\u2014 however, the taste is unpleasant.<\/p>\n\n\n\n<p>To take CBD oils and tinctures, measure out the intended dose using the supplied dropper and place under the tongue for fast onset of effects, or swallow for a slower onset of effects.<\/p>\n\n\n\n<h3>2. CBD Capsules<\/h3>\n\n\n\n<p><a href=\"\/en\/best-cbd\/capsules\/\">CBD capsules<\/a> provide another popular method of consuming CBD. They take away a lot of the guesswork when it comes to dosing and make it easy to take your CBD on the go.<\/p>\n\n\n\n<h3>3. CBD Suppositories<\/h3>\n\n\n\n<p><a href=\"\/en\/best-cbd\/suppositories\/\">CBD suppositories<\/a> are not popular, but they\u2019re an excellent option for addressing inflammation in the digestive tract by delivering the cannabinoids directly to the problematic site.<\/p>\n\n\n\n<h3>4. Topical CBD Products<\/h3>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright is-resized\"><img src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/cbdworld-infammation-3.jpg\" alt=\"\" class=\"wp-image-1507\" width=\"371\" height=\"247\" srcset=\"https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/cbdworld-infammation-3.jpg 1000w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/cbdworld-infammation-3-300x200.jpg 300w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/cbdworld-infammation-3-768x512.jpg 768w\" sizes=\"(max-width: 371px) 100vw, 371px\" \/><\/figure><\/div>\n\n\n\n<p>Any inflammation involving the skin can be relieved by taking CBD internally. However, the best treatment for these conditions is usually <a href=\"\/en\/best-cbd\/cream-for-pain\/\">topical<\/a>. This allows the cannabinoids to concentrate effects on the inflamed local tissues.<\/p>\n\n\n\n<h4>When to Use Topical CBD:<\/h4>\n\n\n\n<ul><li><strong>Psoriasis<\/strong><\/li><li><strong>Eczema<\/strong><\/li><li><strong>Allergic dermatitis<\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/acne\/\">Acne<\/a><\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/muscle-recovery\/\">Muscle injuries<\/a><\/strong><\/li><li><strong>Tendonitis<\/strong><\/li><li><strong>Skin infections<\/strong><\/li><\/ul>\n\n\n\n<h3>5. CBD Edibles<\/h3>\n\n\n\n<p><a href=\"\/en\/best-cbd\/edibles\/\">Edibles<\/a> \u2014&nbsp;including <a href=\"\/en\/best-cbd\/gummies\/\">gummies<\/a>, cookies, or cooking oils \u2014&nbsp;also provide useful ways of getting CBD into the body. They taste great without compromising potency. The only downside is that, with the exception of standardized gummies, it can be challenging to gauge the strength of edibles.&nbsp;Eating too many edibles can have other negative long-term side-effects due to the high sugar content.<\/p>\n\n\n\n<p>Therefore, edibles are better for spot treatment rather than a daily source of CBD.<\/p>\n\n\n\n<h3>6. CBD E-Liquids and Vape Oils<\/h3>\n\n\n\n<p><a href=\"\/en\/best-cbd\/vape-oils\/\">Vaping CBD<\/a> is the most efficient of all the dosage forms because bioavailability through the lungs is much higher than it is through the digestive tract.<\/p>\n\n\n\n<p>However, the cost to start vaping can be steep as you\u2019ll need to buy a vaporizer, and the duration of effects tends to be shorter than that of CBD consumed orally.<\/p>\n\n\n\n<p>Vaping is ideal for delivering CBD to the lungs and is, therefore, a good option for lung inflammation. However, it may or may not make conditions such as asthma worse \u2014 so always use CBD vape oils with caution.<\/p>\n\n\n\n<h2>What&#8217;s The Dose of CBD Oil For Inflammation? <\/h2>\n\n\n\n<p>When it comes to inflammation, the more CBD, the better. Most of the research on using cannabinoids for inflammation indicates a dose-dependent response. This means that the more you take, the stronger the anti-inflammatory effect it produces.<\/p>\n\n\n\n<p>Therefore, the recommended dose will vary according to the level of inflammation.<\/p>\n\n\n\n<p>For low-grade inflammation \u2014 such as early stages of arthritis \u2014 a low strength may achieve the results you\u2019re looking for.<\/p>\n\n\n\n<p>To treat severe inflammation \u2014 such as inflammatory bowel disease or autoimmune diseases \u2014 you may need to opt for a medium or high strength instead.<\/p>\n\n\n\n<h3>General Dosage Guidelines for Inflammatory Conditions<\/h3>\n\n\n\n<div class=\"t-old\"><figure class=\"wp-block-table is-style-regular\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Low-Strength CBD<\/strong><\/td><td><strong>Moderate-Strength CBD<\/strong><\/td><td><strong>High-Strength CBD<\/strong><\/td><\/tr><tr><td>\u2022&nbsp;Early stages of arthritis &nbsp; &nbsp;<br>\u2022&nbsp;Post-viral infection &nbsp; <br>\u2022&nbsp;Low-grade traumatic injury <\/td><td>\u2022&nbsp;Mild allergies &nbsp; &nbsp; <br>\u2022&nbsp;Arthritis &nbsp; <br>\u2022&nbsp;Mild depression <\/td><td>\u2022&nbsp;Multiple sclerosis &nbsp; &nbsp; <br>\u2022&nbsp;Atherosclerosis &nbsp; <br>\u2022&nbsp;Hepatitis &nbsp; <br>\u2022&nbsp;Severe allergies &nbsp; <br>\u2022&nbsp;Moderate depression &nbsp; <br>\u2022&nbsp;Parkinson\u2019s disease <\/td><\/tr><\/tbody><\/table><\/figure><\/div>\n\n\n\n<h4 class=\"has-text-align-center\">CBD Dosage Calculator<\/h4>\n\n\n\n    <div>\n        <div class=\"calc-wr\">\n            <form method=\"post\">\n                <div class=\"calc\" id=\"calculator-17\">\n                    <div class=\"calc--r calc--r-weight\">\n                        <div class=\"calc--lb\"><span class=\"lb-icon lb-icon-weight\"><\/span>Your Weight<\/div>\n                        <div class=\"input-wr\">\n                            <span id=\"weight-sl--vl\"><\/span>\n                            <input type=\"number\" name=\"weight\" value=\"\" min=\"0\" tabindex=\"0\"\/>\n                        <\/div>\n                        <div class=\"calc--u-tabs\">\n                            <input type=\"radio\" id=\"unit-lb\" name=\"unit\" value=\"lb\" class=\"u-t--i\" checked><label for=\"unit-lb\" class=\"u-t--l first\" tabindex=\"1\">lb<\/label>\n                            <input type=\"radio\" id=\"unit-kg\" name=\"unit\" value=\"kg\" class=\"u-t--i\"><label for=\"unit-kg\" class=\"u-t--l\" tabindex=\"2\">kg<\/label>\n                        <\/div>\n                        <div\n                                id=\"weight-slider\"\n                                data-range=\"max\"\n                                data-min=\"0\"\n                                data-max=\"440\"\n                                data-step=\"1\"\n                                data-value=\"\"\n                                data-type=\"\"\n                                class=\"calc--sl\">\n                        <\/div>\n       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type=\"radio\" id=\"strength-heavy\" name=\"strength\" value=\"heavy\" class=\"radio-str--i\"><label for=\"strength-heavy\" class=\"radio-str--l\" tabindex=\"5\">Heavy\n                                <span class=\"lb-tooltip\">Heavy Dose (Chronic pain, Inflammation, Insomnia, Anxiety, Migraines, Epilepsy)<\/span><\/label>\n                        <\/div>\n                    <\/div>\n                    <div class=\"calc--r calc--r-totalcbd\">\n                        <div class=\"calc--lb\"><span class=\"lb-icon lb-icon-totalcbd\"><\/span>Total CBD (optional)<span class=\"ask-tooltip\"><\/span><span class=\"lb-tooltip\">How much CBD is in the bottle (found on the label)?<\/span><\/div>\n                        <div class=\"input-wr\">\n                            <input type=\"number\" name=\"totalcbd\" value=\"\" class=\"input-wr--i\" placeholder=\"500\" tabindex=\"6\">\n                            <span class=\"input-wr--u\">mg<\/span>\n                        <\/div>\n                    <\/div>\n                    <div class=\"calc--r calc--r-volume\">\n                        <div class=\"calc--lb\"><span class=\"lb-icon lb-icon-volume\"><\/span>Volume (optional)<span class=\"ask-tooltip\"><\/span><span class=\"lb-tooltip\">How big is your bottle of CBD?<\/span><\/div>\n                        <div class=\"select-wr\">\n                            <select name=\"volume\" id=\"volume-select\" tabindex=\"7s\">\n                                <option selected value>&#8212;<\/option>\n                                <option value=\"15\">15 mL (0.5 oz)<\/option>\n                                <option value=\"30\">30 mL (1 oz)<\/option>\n                                <option value=\"50\">50 mL (1.7 oz)<\/option>\n                                <option value=\"60\">60 mL (2 oz)<\/option>\n                                <option value=\"120\">120 mL (4 oz)<\/option>\n                            <\/select>\n                        <\/div>\n                    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class=\"embed-wr\"><a href=\"\" class=\"b b--large b--light embed-btn\"><span>Get this calculator<\/span><\/a><\/div>\n            <div class=\"cta-overlay\">\n                <div class=\"cta-modal\">\n                    <div class=\"close-btn\"><\/div>\n                    <div class=\"text-box\">\n                        <p class=\"lead\">Embed this map on your site<\/p>\n                        <p class=\"tagline\">Copy and paste the code below<\/p>\n                    <\/div>\n                    <form>\n                        <textarea id=\"embed\" readonly><script type=\"text\/javascript\">document.write('<iframe src=\"https:\/\/qqbb.click\/c\/d-c\" style=\"border:0;min-height:600px;height:100%;left:0;position:absolute;top:0;width:100%\"><\/iframe>');<\/script><br \/><\/textarea>\n                        <button type=\"button\" value=\"copy\" class=\"b b--large copytoken button\">Copy\n                        <\/button>\n                        <div class=\"cta-tooltip\"><p class=\"cta-tooltip-title\">Successfully copied to clipboard!<\/p>\n                            <p class=\"cta-tooltip-text\">Include this code unmodified to your website to display the calculator.\n                                The widget will appear exactly where you insert the code.\n                                Copy the code, and paste it into your site\\&#8217;s HTML code.<\/p>\n                        <\/div>\n                    <\/form>\n                <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n\n    \n        <script type=\"text\/javascript\">\nwindow.addEventListener('DOMContentLoaded', function() {\n            jQuery(document).ready(function($) {\n                $(this).Calculator(17, false);\n            });\n            });\n\n        <\/script>\n\n    \n\n\n\n<h2>What Are The Side-Effects of CBD? <\/h2>\n\n\n\n<p>Although CBD is proven to be highly safe in terms of toxicity, it\u2019s important to know about the potential <a href=\"http:\/\/dailycbd.com\/en\/cbd-side-effects\/\">side-effects<\/a>. Everybody is different, and what works in one person doesn\u2019t always work the same way in another.<\/p>\n\n\n\n<p><strong>Here are some of the most common side-effects of CBD:<\/strong><\/p>\n\n\n\n<ul><li><strong>Appetite suppression<\/strong><\/li><li><strong>Diarrhea<\/strong><\/li><li><strong>Drowsiness<\/strong><\/li><li><strong>Dry mouth<\/strong><\/li><li><strong>Lightheadedness<\/strong><\/li><li><strong>Lower heart rate<\/strong><\/li><li><strong>Sedation<\/strong><\/li><\/ul>\n\n\n\n<h2>Inflammation 101<\/h2>\n\n\n\n<p>The human body is made up of trillions of individual cells, all working together. Therefore, the cells need to be able to communicate with each other.<\/p>\n\n\n\n<p>We use our nervous system to send messages in the form of electrical impulses to and from our brain, and we use chemical messengers to send signals around the body via the blood.<\/p>\n\n\n\n<p><strong>The process of inflammation relies heavily on these chemical messengers to signal the immune system and regulate blood flow to damaged areas of the body. <\/strong><\/p>\n\n\n\n<p>There are dozens of inflammatory messengers, each sending a particular type of message&nbsp;\u2014 some call immune cells to an area to help clean out the infection, others tell the cardiovascular system to start pooling blood in a damaged area.<\/p>\n\n\n\n<p>Allergic reactions, for example, rely on the activation of the mast cells \u2014 which wait patiently until an allergen floats nearby. When exposed to an allergen, the cell releases a potent dose of inflammatory markers (such as histamine) that cause the cascade of inflammatory reactions that we know as an allergic reaction (for example, hives, runny nose, puffy eyes, or scratchy throat).<\/p>\n\n\n\n<p><strong>Here\u2019s a map of the inflammatory process. Complicated, isn\u2019t it? <\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image\"><img width=\"750\" height=\"863\" src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/cbdworld-inflammation-101.png\" alt=\"\" class=\"wp-image-1262\" srcset=\"https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/cbdworld-inflammation-101.png 750w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/cbdworld-inflammation-101-261x300.png 261w\" sizes=\"(max-width: 750px) 100vw, 750px\" \/><\/figure>\n\n\n\n<p>(Source: Cavaillon et al., 2002)<\/p>\n\n\n\n<p><strong>You may be thinking, \u201cI have no idea what all of this means.\u201d <\/strong><\/p>\n\n\n\n<p>Well, you&#8217;re not alone.<\/p>\n\n\n\n<p>Researchers are still uncovering new information about inflammation, and there are some forms of inflammation that we don\u2019t yet understand (such as interstitial cystitis and irritable bowel syndrome, for example).<\/p>\n\n\n\n<p>The best treatment for inflammation considers the <em>type<\/em> of inflammation.<\/p>\n\n\n\n<p>We need to consider whether the inflammation is acute (short-lived) or chronic (long-lived). We also need to take into account whether the inflammation is caused by physical damage or an allergic or autoimmune reaction. These are essential steps to consider because each of these forms of inflammation involves different chemical messengers.<\/p>\n\n\n\n<p><strong>Stopping inflammation means blocking these chemical messengers. <\/strong><\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright is-resized\"><img src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2020\/02\/shutterstock_718178212.jpg\" alt=\"\" class=\"wp-image-19117\" width=\"344\" height=\"220\"\/><\/figure><\/div>\n\n\n\n<p>The most important distinction to make is whether the inflammation is acute (short-term) or chronic (long-term).<\/p>\n\n\n\n<h3>1. Acute Inflammation<\/h3>\n\n\n\n<p>Acute inflammation refers to short-term inflammation \u2014 typically less than six months in duration. When we get cuts in the skin or stub our toe, we experience acute inflammation. It appears very fast and leaves once the injury has healed.<\/p>\n\n\n\n<p>Acute inflammation can lead to chronic inflammation if the irritant persists (such as eating inflammatory foods on a regular basis).<\/p>\n\n\n\n<p><strong>Common causes of acute inflammation include:<\/strong><\/p>\n\n\n\n<ul><li><strong>Allergic reactions<\/strong><\/li><li><strong>Asthma attacks<\/strong><\/li><li><strong>Traumatic injuries<\/strong><\/li><li><strong>Eczema (can also become chronic)<\/strong><\/li><li><strong>Early stages of arthritis<\/strong><\/li><li><strong>Early stages of depression<\/strong><\/li><\/ul>\n\n\n\n<p>The most critical messengers involved with acute inflammation are histamine, nitric oxide, and inflammatory enzymes such as COX or 5-LOX. Aspirin, for example, works by blocking the COX enzyme.<\/p>\n\n\n\n<p>CBD inhibits the COX enzymes (both COX-1 and COX-2) responsible for producing inflammatory messengers such as leukotrienes and prostaglandins \u2014 known as key mediators in both acute and chronic inflammation [<a href=\"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/34\/5\/34_5_774\/_pdf\">10<\/a>].<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright is-resized\"><img src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2020\/02\/chronic-inflammation-wrist.jpg\" alt=\"\" class=\"wp-image-19118\" width=\"328\" height=\"219\"\/><\/figure><\/div>\n\n\n\n<h3>2. Chronic Inflammation<\/h3>\n\n\n\n<p>Inflammation is categorized as chronic when symptoms continue for longer than six months.<\/p>\n\n\n\n<p>Prolonged inflammation can cause severe damage to the systems affected.<\/p>\n\n\n\n<p><strong>In a nutshell, chronic inflammation works like this:<\/strong><\/p>\n\n\n\n<ol><li><strong>Inflammation damages the tissue<\/strong><\/li><li><strong>The tissue releases new inflammatory messengers to fix the damage<\/strong><\/li><li><strong>The new inflammation causes further damage to the tissue<\/strong><\/li><li><strong>The process repeats<\/strong><\/li><\/ol>\n\n\n\n<p>Over long periods of time, chronic inflammation can lead to other health conditions. Prolonged inflammation may damage membranes (such as the digestive membrane or blood-brain barrier), leads to scar tissue formation, reduce the sensitivity of hormones like insulin, and trigger autoimmune reactions. <\/p>\n\n\n\n<p><strong>Conditions Associated With Chronic Inflammation: <\/strong><\/p>\n\n\n\n<ul><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/anxiety-depression\/\">Depression<\/a><\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/parkinsons-disease\/\">Parkinson\u2019s disease<\/a><\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/multiple-sclerosis\/\">Multiple sclerosis<\/a><\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/arthritis\/\">Arthritis<\/a> (osteoarthritis &amp; rheumatoid arthritis)<\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/colitis-crohns\/\/\">Inflammatory bowel disease<\/a> (Crohn&#8217;s Disease &amp; Ulcerative Colitis)<\/strong><\/li><li><strong>Endometriosis<\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/pcos\/\">Polycystic Ovarian Syndrome<\/a> (PCOS)<\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/pain\/\">Chronic Pain<\/a><\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/anxiety\/\">Anxiety<\/a><\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/anxiety-depression\/\">Mood Disorders<\/a><\/strong><\/li><li><strong><a href=\"http:\/\/dailycbd.com\/en\/best-cbd\/skincare\/\">Eczema &amp; Psoriasis<\/a><\/strong><\/li><\/ul>\n\n\n\n<p>Some of the critical inflammatory messengers involved with chronic inflammation are TNF-a, NF-kB, IL-6, and IFN-y.<strong> CBD has been shown to inhibit all of these inflammatory messengers.<\/strong><\/p>\n\n\n\n<h2>Conventional Inflammation Treatment<\/h2>\n\n\n\n<p>Inflammation is very common \u2014 as a result, we\u2019ve developed many different approaches to treating inflammation over the years.<\/p>\n\n\n\n<p><strong>Some common forms of inflammation treatment include:<\/strong><\/p>\n\n\n\n<h3>1. Dietary Changes<\/h3>\n\n\n\n<ul><li><strong>Eliminate inflammatory-causing foods<\/strong><\/li><li><strong>Identify and eliminate sources of food allergies<\/strong><\/li><li><strong>Increase fiber and antioxidant-rich foods<\/strong><\/li><li><strong>Increase anti-inflammatory foods<\/strong> <strong>(such as turmeric or ginger)<\/strong><\/li><\/ul>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright is-resized\"><img src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2020\/02\/inflammation-yoga.jpg\" alt=\"\" class=\"wp-image-19119\" width=\"355\" height=\"237\"\/><\/figure><\/div>\n\n\n\n<h3>2. Anti-inflammatory Medications<\/h3>\n\n\n\n<ul><li><strong>Corticosteroids<\/strong><\/li><li><strong>NSAIDs<\/strong> <a href=\"http:\/\/dailycbd.com\/en\/drug-interactions\/aspirin\/\" target=\"_blank\" rel=\"noopener\"><strong>(Aspirin,<\/strong><\/a> Ibuprofen, and Acetaminophen)<\/li><li><strong>TNF inhibitors<\/strong> <strong>(Adalimumab, and Etanercept)<\/strong><\/li><\/ul>\n\n\n\n<h3>3. Herbal Supplements<\/h3>\n\n\n\n<ul><li><strong>Cannabis extracts<\/strong> <strong>(CBD, <a href=\"http:\/\/dailycbd.com\/en\/cbn\/\">CBN<\/a>, and THC)<\/strong><\/li><li><strong>Ginger root (<em>Zingiber officinalis<\/em>)<\/strong><\/li><li><strong>Frankincense resin (<em>Boswellia serrata<\/em>)<\/strong><\/li><li><strong>Turmeric root<\/strong> <strong>(<em>Curcuma longa<\/em>)<\/strong><\/li><li><strong>Aloe<\/strong> <strong>(<em>Aloe vera<\/em>)<\/strong><\/li><\/ul>\n\n\n\n<h3>4. Lifestyle Changes<\/h3>\n\n\n\n<ul><li><strong>Gentle aerobic exercise<\/strong><\/li><li><strong>Stress reduction techniques<\/strong><\/li><li><strong>Yoga\/meditation<\/strong><\/li><li><strong>Sleep hygiene<\/strong><\/li><\/ul>\n\n\n\n<h2>CBD For Inflammation: What The Research Says<\/h2>\n\n\n\n<p>CBD is a potent anti-inflammatory \u2014 interfering with inflammatory messengers at almost every level of the inflammatory response.<\/p>\n\n\n\n<p><strong>There are a few reasons why CBD can infiltrate and halt inflammation at so many levels:<\/strong><\/p>\n\n\n\n<ol><li><strong>It stops the breakdown of anandamide<\/strong> <strong>\u2014&nbsp;<\/strong>a powerful regulator of inflammation throughout the body.<\/li><li><strong>CBD (and other cannabinoids) are structurally similar to many of our inflammatory messengers<\/strong> <strong>(similar to our prostaglandins and leukotrienes).<\/strong><\/li><li><strong>CBD activates the vanilloid receptors<\/strong> <strong>\u2014 <\/strong>responsible for regulating a different set of inflammatory messengers (TNF-a, IL-4, IL-12) [<a href=\"https:\/\/www.jstage.jst.go.jp\/article\/jphs\/advpub\/0\/advpub_09295SC\/_pdf\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a>].<\/li><li><strong>It slows the activation of immune cells&nbsp;such as T and B cells [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2828614\/?__hstc=209342221.653140fecad23cdf89637a97c833078f.1463875200047.1463875200048.1463875200049.1&amp;__hssc=209342221.1.1463875200050&amp;__hsfp=1314462730\" target=\"_blank\" rel=\"noreferrer noopener\">1<\/a>] \u2014 <\/strong>responsible for maintaining autoimmune-related inflammation.<\/li><li><strong>CBD triggers apoptosis<\/strong>&nbsp;<strong>(programmed cell death) in the immune cells involved with chronic inflammation [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2828614\/?__hstc=209342221.653140fecad23cdf89637a97c833078f.1463875200047.1463875200048.1463875200049.1&amp;__hssc=209342221.1.1463875200050&amp;__hsfp=1314462730\">1<\/a>]<\/strong><\/li><\/ol>\n\n\n\n<h3>What Inflammatory Messengers Does CBD Interact With?<\/h3>\n\n\n\n<p>Unlike most anti-inflammatory compounds that inhibit a select few of the inflammatory messengers driving inflammation, CBD stops almost all of them.<\/p>\n\n\n\n<p>This makes it useful for many different types of inflammation \u2014 from allergic reactions and autoimmunity to sprains and strains.<\/p>\n\n\n\n<h4>Inflammatory Messengers Affected by CBD<\/h4>\n\n\n\n<div class=\"t-old\"><figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Inflammatory Messenger<\/strong><\/td><td><strong>Role in Inflammation<\/strong><\/td><td><strong>Inhibiting Cannabinoids<\/strong><\/td><\/tr><tr><td><strong>Histamine<\/strong><\/td><td>Involved in allergic reactions and triggers rapid inflammation<\/td><td>THC [<a href=\"https:\/\/link.springer.com\/article\/10.1007\/s00011-003-1162-z\">6<\/a>]<\/td><\/tr><tr><td><strong>IFN-\u03b3<\/strong><\/td><td>Heavily involved in sustaining chronic inflammation<\/td><td>CBD [<a href=\"http:\/\/www.druglibrary.net\/crl\/immune\/Srivastava_et.al_98_Cytokine_Production_Immunopharmacol.pdf\">5<\/a>]<\/td><\/tr><tr><td><strong>NF-kB<\/strong><\/td><td>One of the key sustaining factors for psoriasis and involved with cancer growth<\/td><td>CBD [<a href=\"http:\/\/www.jbc.org\/content\/285\/3\/1616.full.pdf\">7<\/a>]<\/td><\/tr><tr><td><strong>TNF-\u03b1<\/strong><\/td><td>Triggers systemic (whole-body) inflammation<\/td><td>CBD [<a href=\"http:\/\/downloads.hindawi.com\/journals\/mi\/2015\/538670.pdf\">8<\/a>]THC [<a href=\"https:\/\/www.jstage.jst.go.jp\/article\/jphs\/advpub\/0\/advpub_09295SC\/_pdf\">2<\/a>]<\/td><\/tr><tr><td><strong>IL-2<\/strong><\/td><td>Involved with inflammation related to cancer and autoimmune disease<\/td><td>THC<br>CBN [<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0041008X03000103\">4<\/a>]<\/td><\/tr><tr><td><strong>IL-4<\/strong><\/td><td>Regulates conversion of T-helper cells to Th2 cells and is heavily involved with autoimmunity<\/td><td>CBD [<a href=\"http:\/\/downloads.hindawi.com\/journals\/mi\/2015\/538670.pdf\">8<\/a>]THC [<a href=\"https:\/\/www.jstage.jst.go.jp\/article\/jphs\/advpub\/0\/advpub_09295SC\/_pdf\">2<\/a>]CBN [<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0041008X03000103\">4<\/a>]<\/td><\/tr><tr><td><strong>IL-6<\/strong><\/td><td>Triggers inflammatory cascade in acute inflammation and is a sustaining factor in chronic inflammation and autoimmunity<\/td><td>CBD [<a href=\"http:\/\/downloads.hindawi.com\/journals\/mi\/2015\/538670.pdf\">8<\/a>]<\/td><\/tr><tr><td><strong>IL-8<\/strong><\/td><td>Involved in acute inflammation from infectious diseases (viruses or bacteria)<\/td><td>CBD [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2748879\/\">9<\/a>]<\/td><\/tr><tr><td><strong>IL-12<\/strong><\/td><td>Involved in autoimmune conditions, including rheumatoid arthritis<\/td><td>CBD [<a href=\"https:\/\/www.jstage.jst.go.jp\/article\/jphs\/advpub\/0\/advpub_09295SC\/_pdf\">2<\/a>]<\/td><\/tr><tr><td><strong>IL-13<\/strong><\/td><td>Both inflammatory <em>and<\/em> anti-inflammatory depending on the other messengers involved<\/td><td>THC<br>CBN [<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0041008X03000103\">4<\/a>]CBD [<a href=\"http:\/\/downloads.hindawi.com\/journals\/mi\/2015\/538670.pdf\">8<\/a>]<\/td><\/tr><tr><td><strong>Prostaglandins<\/strong><\/td><td>One of the key regulators in starting and maintaining the inflammatory response<\/td><td>CBD [<a href=\"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/34\/5\/34_5_774\/_pdf\">10<\/a>]<\/td><\/tr><tr><td><strong>Leukotrienes<\/strong><\/td><td>One of the key regulators in starting and maintaining the inflammatory response<\/td><td>CBD [<a href=\"https:\/\/www.jstage.jst.go.jp\/article\/bpb\/34\/5\/34_5_774\/_pdf\">10<\/a>]<\/td><\/tr><\/tbody><\/table><\/figure><\/div>\n\n\n\n<p>As you can see, CBD and many of the other cannabinoids have a lot to offer regarding inflammation \u2014 for a variety of different <em>types <\/em>of inflammation.<\/p>\n\n\n\n<p>Because there are other cannabinoids with their specific anti-inflammatory effects,<strong> it\u2019s best to find a full-spectrum extract for treating inflammatory conditions<\/strong>&nbsp;rather than a pure CBD extract.<\/p>\n\n\n\n<h2>Final Verdict: Using CBD for Inflammation<\/h2>\n\n\n\n<p>CBD is an excellent anti-inflammatory supplement \u2014 and as a result, it is used for many different types of inflammation.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright is-resized\"><img src=\"http:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/inflammation-knee-arthritis.jpg\" alt=\"\" class=\"wp-image-2175\" width=\"393\" height=\"262\" srcset=\"https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/inflammation-knee-arthritis.jpg 1000w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/inflammation-knee-arthritis-300x200.jpg 300w, https:\/\/dailycbd.com\/en\/wp-content\/uploads\/sites\/7\/2018\/11\/inflammation-knee-arthritis-768x511.jpg 768w\" sizes=\"(max-width: 393px) 100vw, 393px\" \/><\/figure><\/div>\n\n\n\n<p><strong>Types of inflammation CBD works for:<\/strong><\/p>\n\n\n\n<ul><li><strong>Autoimmunity<\/strong><\/li><li><strong>Allergic reactions<\/strong><\/li><li><strong>Traumatic soft tissue injuries<\/strong><\/li><li><strong>Muscle strains<\/strong><\/li><li><strong>Inflammatory bowel disease<\/strong><\/li><li><strong>Atherosclerosis<\/strong><\/li><li><strong>Post-surgery inflammation<\/strong><\/li><\/ul>\n\n\n\n<p>The key to using CBD effectively for inflammation is to ensure you&#8217;re only using high-quality, full-spectrum extracts that have been confirmed to be free from contaminants through third-party testing.<\/p>\n\n\n\n<p>You can use virtually any form of CBD to get anti-inflammatory benefits, but we recommend finding a high-potency oil due to the simplicity of use, cost-effectiveness, and long shelf-life.<\/p>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n\n\n\n<h2>References Cited in This Article<\/h2>\n\n\n\n<ol><li>Nagarkatti, P., Pandey, R., Rieder, S. A., Hegde, V. L., &amp; Nagarkatti, M. (2009). Cannabinoids as novel anti-inflammatory drugs. Future medicinal chemistry, 1(7), 1333-1349.<\/li><li>Tsuji, F., Murai, M., Oki, K., Inoue, H., Sasano, M., Tanaka, H., &#8230; &amp; Aono, H. (2010). Effects of SA13353, a transient receptor potential vanilloid 1 agonist, on leukocyte infiltration in lipopolysaccharide-induced acute lung injury and ovalbumin-induced allergic airway inflammation. Journal of pharmacological sciences, 112(4), 487-490.<\/li><li>Derocq, J. M., Jbilo, O., Bouaboula, M., S\u00e9gui, M., Cl\u00e8re, C., &amp; Casellas, P. (2000). Genomic and Functional Changes Induced by the Activation of the Peripheral Cannabinoid Receptor CB2 in the Promyelocytic Cells HL-60 Possible Involvement of the CB2 Receptor in Cell Differentiation. Journal of Biological Chemistry, 275(21), 15621-15628.<\/li><li>Jan, T. R., Farraj, A. K., Harkema, J. R., &amp; Kaminski, N. E. (2003). Attenuation of the ovalbumin-induced allergic airway response by cannabinoid treatment in A\/J mice\u2606. Toxicology and applied pharmacology, 188(1), 24-35.<\/li><li>Srivastava, M. D., Srivastava, B. I. S., &amp; Brouhard, B. (1998). \u03949 tetrahydrocannabinol and cannabidiol alter cytokine production by human immune cells. Immunopharmacology, 40(3), 179-185.<\/li><li>Dvorak, M., Watkinson, A., McGlone, F., &amp; Rukwied, R. (2003). Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin. Inflammation research, 52(6), 238-245.<\/li><li>Kozela, E., Pietr, M., Juknat, A., Rimmerman, N., Levy, R., &amp; Vogel, Z. (2010). Cannabinoids \u03949-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-\u03baB and interferon-\u03b2\/STAT proinflammatory pathways in BV-2 microglial cells. Journal of biological chemistry, 285(3), 1616-1626.<\/li><li>Vuolo, F., Petronilho, F., Sonai, B., Ritter, C., Hallak, J. E., Zuardi, A. W., &#8230; &amp; Dal-Pizzol, F. (2015). Evaluation of serum cytokines levels and the role of cannabidiol treatment in animal model of asthma. Mediators of inflammation, 2015.<\/li><li>Kaplan, B. L., Springs, A. E., &amp; Kaminski, N. E. (2008). The profile of immune modulation by cannabidiol (CBD) involves deregulation of nuclear factor of activated T cells (NFAT). Biochemical pharmacology, 76(6), 726-737.<\/li><li>Ruhaak, L. R., Felth, J., Karlsson, P. C., Rafter, J. J., Verpoorte, R., &amp; Bohlin, L. (2011). Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa. Biological and Pharmaceutical Bulletin, 34(5), 774-778.<\/li><\/ol>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Inflammation is at the root of many medical conditions. <\/p>\n<p>CBD oil has an impressive anti-inflammatory profile. <\/p>\n<p>Here&#8217;s how it works. <\/p>\n","protected":false},"author":10,"featured_media":680,"parent":0,"menu_order":47,"template":"","crb_condition_category":[40,45,2832,46,48,49,2830,42,43,44],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>CBD Oil For Inflammation: What The Research Says \u2014 Daily CBD<\/title>\n<meta name=\"description\" content=\"CBD has proven anti-inflammatory benefits through its effects on the ECS. 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